Evidence map›Paper›PMID 33009956›Full record

ReviewCurrent treatment options in oncology2020

Late and Long-Term Treatment-Related Effects and Survivorship for Head and Neck Cancer Patients.

Marci Lee Nilsen, Michael A Belsky, Nicole Scheff, Jonas T Johnson, Dan P Zandberg, Heath Skinner, Robert Ferris

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current treatment options in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Post-traumatic growth and cancer survivorship: experiences of living with treatment-related impairment.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Oral health-related quality of life among long-term head and neck cancer survivors: a multinational study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  7. Clinical and social determinants of survivorship clinic attendance in head and neck cancer.Journal of cancer survivorship : research and practice · 2025
    Article
  8. Prevalence of function-limiting late effects in survivors of head and neck cancer.PM & R : the journal of injury, function, and rehabilitation · 2025
    Article
  9. Late radiation-associated dysphagia following treatment for head and neck cancer: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  10. Review
  11. Article
  12. Article
  13. From Ramsay Hunt to Parotid Cancer: A Case Report.ORL-head and neck nursing : official journal of the Society of Otorhinolaryngology and Head-Neck Nurses · 2024
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Head and Neck Cancers Medical Costs in a Universal Health System: A Population-Based Case-Control Study.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Marci Lee NilsenSchool of Nursing, Department of Acute and Tertiary Care, University of Pittsburgh, 318A Victoria Building, 3500 Victoria Street, Pittsburgh, PA, 15261, USA. Mlf981@pitt.edu.
Michael A BelskySchool of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
Nicole ScheffSchool of Medicine, Department of Neurobiology, University of Pittsburgh, Pittsburgh, PA, USA.
Jonas T JohnsonSchool of Medicine, Department of Otolaryngology, University of Pittsburgh, Pittsburgh, PA, USA.
Dan P ZandbergDivision of Hematology/Oncology, UPMC Hillman Cancer Center, Pittsburgh, PA, USA.
Heath SkinnerSchool of Medicine, Department of Radiation Oncology, University of Pittsburgh, Pittsburgh, PA, USA.
Robert FerrisUPMC Hillman Cancer Center, Pittsburgh, PA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

opinion statementThe demographics of head and neck cancer (HNC) survivors are changing, contributing to a growing number of survivors and a greater length of survivorship. Curative treatment involves intense multimodal therapy, which contributes to both short-term toxicities and long-term treatment-related effects. Delivering high-quality, relevant cancer survivorship care is a growing national priority. Various survivorship models and tools, such as survivorship care plans, have been utilized in an attempt to enhance care and optimize outcomes. However, an essential, yet understudied, component of high-quality survivorship care is the identification and management of late and long-term treatment-related effects. In this article, we will describe the current advancements in survivorship care as well as the research related to late and long-term treatment effects. While there is a growing body of literature that describes the prevalence of treatment-related effects and their impact on quality of life, more work is needed. Research that investigates the interplay of these complex treatment effects, the biological mechanisms that contribute to their variability, and interventions designed to mitigate them are desperately needed. While de-intensification offers the potential to alleviate these effects for future survivors, we need clinically meaningful assessment tools and therapies to provide the survivors we evaluate and treat daily. Targeted patient-reported outcomes and objective measures validated through clinical research are needed to help us systematically identify and treat late and long-term effects. In order to tailor and optimize the care we provide to our HNC survivors, we will need to leverage these tools as well as the expertise of all members of our multidisciplinary survivorship teams.

Indexed as

AnimalsCancer SurvivorsHead and Neck NeoplasmsHumansPatient Reported Outcome MeasuresQuality of Health CareQuality of LifeSurvivorshipHead and neck cancerSurvivorshipToxicitiesTreatment effects

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.