Evidence map›Paper›PMID 33009927›Full record

ArticleChild's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery2021

Optic nerve sheath diameter does not correlate with intracranial pressure in pediatric neurocritical care patients.

Austin Biggs, Marlina Lovett, Melissa Moore-Clingenpeel, Nicole O'Brien

Abstract read
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In one paragraph

Article in Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Observational
  2. Evaluation of optic nerve sheath diameter measurements in postictal pediatric patients.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024
    Article
  3. Article
  4. Article
  5. Optic Nerve Ultrasound Evaluation in Children: A Review.Diagnostics (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Utility of optic nerve sheath diameter in intracranial pressure: can we hang on it?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2021
    Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Austin BiggsDivision of Pediatric Critical Care, Medical University of South Carolina, Charleston, SC, USA. Austin.Biggs@gmail.com.ORCID 0000-0002-1434-9137
Marlina LovettDivision of Critical Care, Nationwide Children's Hospital, Columbus, OH, USA.
Melissa Moore-ClingenpeelDivision of Critical Care, Nationwide Children's Hospital, Columbus, OH, USA.
Nicole O'BrienDivision of Critical Care, Nationwide Children's Hospital, Columbus, OH, USA.
Nationwide Children's Hospital · USMedical University of South Carolina · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIntracranial pressure (ICP) > 20 mmHg is associated with worse outcomes in children. The gold standard for monitoring ICP is invasive, has complications such as bleeding and infection, and may not be available in resource limited areas. Ultrasound of the optic nerve sheath diameter (ONSD) has been studied as a noninvasive way to evaluate for elevated ICP in adults. Its utility in pediatrics remains unclear.

methodsA prospective study was performed in a pediatric intensive care unit in children ≤ 18 years old. ONSD ultrasound was performed using a 13-6 MHz linear probe with the patient's invasively measured ICP simultaneously recorded. Linear mixed effects models were used to evaluate the association between ONSD and ICP.

resultsOne hundred thirty-six measurements were obtained from 16 patients. ONSD was not significantly associated with ICP (p = 0.51). A ROC curve assessing ONSD to determine elevated ICP > 20 mmHg had an area under the curve of 0.52 (95%CI = 0.32-0.72). There was no difference in measurements obtained between the left and right ONSD at the same time (p = 0.82).

conclusionsIn conclusion, this study demonstrated no association between ONSD measurement and invasively monitored ICP in critically ill children.

Indexed as

Intracranial HypertensionIntracranial PressureAdolescentAdultChildHumansOptic NerveProspective StudiesSensitivity and SpecificityUltrasonographyCritical careIntracranial pressureOptic nerve sheath diameterPICUUltrasound

Identifiers

PMID33009927
OpenAlexW3090063041

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.