Evidence map›Paper›PMID 33009893›Full record

ReviewPediatric blood & cancer2020

Hematological manifestations of SARS-CoV-2 in children.

Chrysoula Kosmeri, Epameinondas Koumpis, Sophia Tsabouri, Ekaterini Siomou, Alexandros Makis

Open access · bronzeAbstract readReview
In one paragraph

Review in Pediatric blood & cancer, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
1.9field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 93 citations in OpenAlex.

  1. Article
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  10. Biology of Anemia: A Public Health Perspective.The Journal of nutrition · 2023
    Article
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  13. Review
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  20. Severe Acute Respiratory Syndrome Coronavirus 2 Infections in Children.Infectious disease clinics of North America · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Chrysoula KosmeriDepartment of Pediatrics, Faculty of Medicine, University of Ioannina, Ioannina, Greece.ORCID 0000-0003-1244-375X
Epameinondas KoumpisDepartment of Internal Medicine, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Sophia TsabouriDepartment of Pediatrics, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Ekaterini SiomouDepartment of Pediatrics, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
Alexandros MakisDepartment of Pediatrics, Faculty of Medicine, University of Ioannina, Ioannina, Greece.
University of Ioannina · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), though mainly a respiratory disease, can impair many systems, including causing hematological complications. Lymphopenia and hypercoagulability have been reported in adults with coronavirus disease 2019 (COVID-19) and are considered markers of poor prognosis. This review summarizes the hematological findings in children with SARS-CoV-2 infection. The majority of infected children had a normal leukocyte count, while the most common white blood cell abnormality was leukopenia. Lymphopenia, which may be a marker of severe disease, was rarer in children than in adults, possibly due to their immature immune system or due to the less severe manifestation of COVID-19 in this age group. Age may have an impact, and in neonates and infants the most common abnormality was lymphocytosis. Abnormalities of red blood cells and platelets were uncommon. Anemia and hypercoagulability were reported mainly in children presenting the novel multisystem inflammatory syndrome (MIS) associated with SARS-CoV-2.

Indexed as

PandemicsAdolescentAnemiaBetacoronavirusBiomarkersBlood PlateletsChildChild, PreschoolCoronavirus InfectionsCOVID-19ErythrocytesFemaleHumansInfantInfant, NewbornLeukocyte CountBiomarkerschildrenCOVID-19hematological manifestationsMISSARS-CoV-2

Identifiers

PMID33009893
PMCPMC7646039
OpenAlexW3089858402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.