Evidence map›Paper›PMID 33009835›Full record

ArticleJournal of veterinary internal medicine2020

Aventriculi associated with holoprosencephaly in a dog.

Laura Barnard, Alexane Durand, Lauren Blume, Laura Lee, Starr Cameron

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Polymicrogyria, aventriculy, polydactyly, encephalocele, callosal agenesis (PAPEC): a new syndrome?Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022
    Article
  2. Aprosopia/holoprosencephaly in a stillborn puppy: when the face predicts the brain.International journal of veterinary science and medicine · 2021
    Article
  3. Aventriculi associated with holoprosencephaly in a dog.Journal of veterinary internal medicine · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Laura BarnardCanada West Veterinary Specialists, Vancouver, British Columbia, Canada.
Alexane DurandDepartment of Clinical Veterinary Sciences, University of Bern, Bern, Switzerland.
Lauren BlumeVeterinary Imaging Solutions LLC, Milton, Vermont, USA.
Laura LeeDepartment of Pathological Sciences, University of Madison - Wisconsin, Madison, Wisconsin, USA.
Starr CameronDepartment of Medical Sciences, University of Wisconsin - Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0001-5009-2546
University of Wisconsin–Madison · USCollege of Pharmacists of British Columbia · CAUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

case descriptionA 10-month-old neutered male mixed breed dog was presented for assessment of poorly controlled seizures. CLINICAL

findingsMagnetic resonance imaging of the brain disclosed complete absence of the lateral and third ventricles and mesencephalic aqueduct. Postmortem computed tomographic (CT) imaging and positive contrast cisterno-ventriculography confirmed the lack of a contiguous ventricular system. However, histopathology identified the presence of vestigial lateral and third ventricles with hypoplastic choroid plexus, atresia of the third ventricle, and fused thalami, consistent with a diagnosis of lobar holoprosencephaly (HPE). CLINICAL RELEVANCE: To our knowledge, this report is the first case of radiographically confirmed aventriculi associated with HPE, a rare congenital malformation previously reported in people, to be described in veterinary medicine.

Indexed as

Dog DiseasesHoloprosencephalyAnimalsBrainCerebral VentriclesChoroid PlexusDogsMagnetic Resonance ImagingMalecongenitalmalformationneuropathologyventriclesventriculogram

Identifiers

PMID33009835
PMCPMC7694808
OpenAlexW3089675386

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.