Evidence map›Paper›PMID 33009685›Full record

Trial reportAddiction (Abingdon, England)2021

Reconsidering alcohol treatment non-responders: psychosocial functioning among heavy drinkers 3 years following treatment.

Matthew R Pearson, Adam D Wilson, Dylan K Richards, Katie Witkiewitz

Abstract readClinical TrialMulticenter Study
In one paragraph

Trial report in Addiction (Abingdon, England), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Matthew R PearsonCenter on Alcohol, Substance use, and Addictions, University of New Mexico, Albuquerque, NM, USA.ORCID 0000-0003-3772-0186
Adam D WilsonCenter on Alcohol, Substance use, and Addictions, Department of Psychology, University of New Mexico, Albuquerque, NM, USA.
Dylan K RichardsCenter on Alcohol, Substance use, and Addictions, University of New Mexico, Albuquerque, NM, USA.
Katie WitkiewitzCenter on Alcohol, Substance use, and Addictions, Department of Psychology, University of New Mexico, Albuquerque, NM, USA.ORCID 0000-0002-1086-3067

Funding

Alcohol Research Training: Methods & MechanismsT32AA018108 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2010 to 2026
$5.6M
Precision Medicine and Recovery in a Telehealth Treatment Program for Alcohol Use DisorderR01AA022328 · NIAAA · UNIVERSITY OF NEW MEXICO · PI Katie A Witkiewitz · 2013 to 2026
$3.1M
Efficacy and neurobiological mechanisms of mobile-delivered cognitive retrainingK01AA023233 · NIAAA · UNIVERSITY OF NEW MEXICO · PI PEARSON, MATTHEW RYAN · 2014 to 2018
$832k
An Ecologically Valid Application of Self-Determination Theory to Understand Responsible Alcohol UseF32AA028712 · NIAAA · UNIVERSITY OF NEW MEXICO · PI RICHARDS, DYLAN K · 2020 to 2022
$189k
The role of brain-derived neurotrophic factor in the link between physical activity and psychosocial recovery from alcohol use disorderF31AA026773 · NIAAA · UNIVERSITY OF NEW MEXICO · PI WILSON, ADAM DEFOREST · 2018 to 2019
$71k
NIAAA NIH HHS F31 AA026773NIAAA NIH HHS F32 AA028712NIAAA NIH HHS K01 AA023233NIAAA NIH HHS R01 AA022328NIAAA NIH HHS T32 AA018108
6 · The paper itself

Abstract

BACKGROUND AND

aimsPsychosocial functioning among individuals who exceed low-risk drinking limits (exceed three to four standard drinks for women/men) is heterogeneous. Among those who receive treatment for alcohol use disorder (AUD), recent research found that more than one-half of those who exceeded low-risk limits (i.e. treatment non-responders) reported good psychosocial functioning, commensurate with those who were abstinent or low-risk drinkers (i.e. treatment responders) up to 1 year following treatment. This study aimed to determine if good levels of psychosocial functioning are maintained beyond 1 year.

designSecondary analysis of 3-year follow-up data from Project MATCH (Matching Alcoholism Treatment to Client Heterogeneity) and the Combined Pharmacotherapies and Behavioral Interventions study (COMBINE), multi-site alcohol clinical trials conducted in the United States.

settingEleven sites in COMBINE and nine sites in Project MATCH.

participantsIndividuals with AUD from COMBINE and Project MATCH (n = 1383 and n = 1726) characterized in terms of drinking/functioning at 1-year follow-up and retained at 3-year (n = 641 and n = 790) post-treatment follow-ups. MEASUREMENTS: Alcohol consumption measured by Form-90 and psychosocial functioning assessed by various instruments at 3 years post-treatment

findingsHigh-functioning non-responders at 1 year post-treatment maintained a high level of functioning 2 years later and were not significantly different from the abstainers/low-risk drinkers on any functional outcomes (e.g. SF12 Mental Health Mean difference: -1.38 [95% confidence interval (CI) = -4.34, 1.57), SF12 Physical Health Mean difference: -0.43 (95% CI = -2.28, 3.13)].

conclusionsApproximately one-half of those who engage in some heavy drinking in the year following treatment for alcohol use disorder appear to maintain high levels of psychosocial functioning up to 3 years following treatment.

Indexed as

Alcoholic IntoxicationAlcoholismAlcohol DrinkingBehavior TherapyFemaleHumansMalePsychosocial FunctioningTreatment OutcomeUnited StatesAlcohol treatmentalcohol use disorderheavy drinkinglatent profile analysispsychosocial functioningtreatment response

Identifiers

PMID33009685
PMCPMC8017002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.