Evidence map›Paper›PMID 33009682›Full record

ArticleJournal of veterinary internal medicine2020

Risk factors for enterococcal bacteriuria in dogs: A retrospective study.

Michael W Wood, Adam Lepold, Dahlia Tesfamichael, Michael R Lasarev

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Occurrence of Antimicrobial-ResistantAntibiotics (Basel, Switzerland) · 2024
    Article
  4. Review
  5. Risk factors of enterococcal bacteriuria in cats: A retrospective study.The Canadian veterinary journal = La revue veterinaire canadienne · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Characterization and Comparison ofAnimals : an open access journal from MDPI · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Michael W WoodDepartment of Medical Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID https://orcid.org/0000-0002-6142-4769
Adam LepoldSchool of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Dahlia TesfamichaelCollege of Letters and Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Michael R LasarevDepartment of Biostatistics and Medical Informatics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Wisconsin–Madison · US

Funding

University of Wisconsin Institute for Clinical and Translational ResearchUL1TR002373 · NCATS · UNIVERSITY OF WISCONSIN-MADISON · PI ELIZABETH S BURNSIDE, Allan R. Brasier · 2017 to 2026
$75.9M
Short-Term Research Training of Veterinary Students in WisconsinT35OD011078 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI BJORLING, DALE EDMOND, JORGENSEN, JOAN S · 2012 to 2025
$1.0M
Clinical and Translational Science Award (CTSA) program, through the NIH National Center for Advancing Translational Sciences UL1TR002373NCATS NIH HHS UL1 TR002373NIH HHS T35 OD011078
6 · The paper itself

Abstract

backgroundIn humans, Enterococcus spp. urinary tract infections (UTI) are commonly associated with urinary catheter-induced urothelial inflammation but this is not the case in dogs. HYPOTHESIS/

objectivesTo identify risk factors predisposing dogs to enterococcal bacteriuria. ANIMALS: Seventy dogs with Enterococcus spp. bacteriuria (case) and 70 dogs with Enterococcus coli bacteriuria (control).

methodsA single center retrospective case-control study with subjects and controls identified by a medical records search for Enterococcus spp. (subject) or E coli (control) bacteriuria from January 1, 2014 to December 31, 2017. Cases and controls were balanced with respect to average age and weight. Binary logistic regression was used to estimate and test whether the odds of having Enterococcus spp. bacteriuria (instead of E coli) were associated with the presence of any given characteristic.

resultsA history of recurrent bacteriuria was significantly more common in Enterococcus spp. cases than in E coli controls (odds ratio [OR]: 2.07; 95% confidence interval [CI]: 1.04-4.16, P = .04). Comorbidities associated with the presence of Enterococcus spp. bacteriuria included lower urinary tract (LUT) anatomic abnormalities (OR: 2.94; 95% CI: 1.17-8.10, P = .02), urolithiasis (P = .01), and the presence of LUT neoplasia (P = .04). Small frequencies (n = 12 and n = 6, respectively) compromise our ability to precisely estimate the genuine OR for the latter 2 characteristics. CONCLUSIONS AND CLINICAL IMPORTANCE: If the identified risk factors promote Enterococcus spp. colonization in dogs via induced LUT inflammation similar to people then Enterococcus spp. bacteriuria could be a sentinel for underlying LUT inflammation.

Indexed as

BacteriuriaDog DiseasesUrinary Tract InfectionsAnimalsCase-Control StudiesDogsEnterococcusEscherichia coliRetrospective StudiesRisk FactorscystitisEnterococcus faecalisEnterococcus faeciumurinary tract infection

Identifiers

PMID33009682
PMCPMC7694861
OpenAlexW3089474258

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.