Evidence map›Paper›PMID 33009594›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2021

Increased pulmonary serotonin transporter in patients with chronic obstructive pulmonary disease who developed pulmonary hypertension.

Armin Frille, Michael Rullmann, Georg-Alexander Becker, Marianne Patt, Julia Luthardt, Solveig Tiepolt, Hubert Wirtz, Osama Sabri, Swen Hesse, Hans-Juergen Seyfarth

Open access · hybridAbstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Armin Frille *Department of Respiratory Medicine, University Hospital Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.ORCID https://orcid.org/0000-0003-2843-3863
Michael Rullmann *Integrated Research and Treatment Center (IFB) Adiposity Diseases, University Medical Center Leipzig, 04013, Leipzig, Germany.ORCID https://orcid.org/0000-0002-2683-9432
Georg-Alexander BeckerDepartment of Nuclear Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.
Marianne PattDepartment of Nuclear Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.
Julia LuthardtDepartment of Nuclear Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.
Solveig TiepoltDepartment of Nuclear Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.ORCID https://orcid.org/0000-0003-0378-8334
Hubert WirtzDepartment of Respiratory Medicine, University Hospital Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany.
Osama SabriDepartment of Nuclear Medicine, University Hospital Leipzig, 04103, Leipzig, Germany.
Swen Hesse *Integrated Research and Treatment Center (IFB) Adiposity Diseases, University Medical Center Leipzig, 04013, Leipzig, Germany.
Hans-Juergen Seyfarth *Department of Respiratory Medicine, University Hospital Leipzig, Liebigstrasse 20, 04103, Leipzig, Germany. hans-juergen.seyfarth@medizin.uni-leipzig.de.
University Hospital Leipzig · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePulmonary hypertension (PH) is characterized by a progressive remodelling of the pulmonary vasculature resulting in right heart failure and eventually death. The serotonin transporter (SERT) may be involved in the pathogenesis of PH in patients with chronic-obstructive pulmonary disease (COPD). This study investigated for the first time the SERT in vivo availability in the lungs of patients with COPD and PH (COPD+PH).

methodsSERT availability was assessed using SERT-selective [

results[

conclusionBy applying [

Indexed as

Hypertension, PulmonaryPulmonary Disease, Chronic ObstructiveHumansLungPositron Emission Tomography Computed TomographySerotonin Plasma Membrane Transport ProteinsSerotonin Plasma Membrane Transport ProteinsChronic obstructive pulmonary diseaseComputed tomographyPositron emission tomographyPulmonary hypertensionSerotonin transporter

Identifiers

PMID33009594
PMCPMC8041706
OpenAlexW3090811422

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.