Evidence map›Paper›PMID 33009447›Full record

ArticleScientific reports2020

Functional parcellation of the hippocampus by semi-supervised clustering of resting state fMRI data.

Hewei Cheng, Hancan Zhu, Qiang Zheng, Jie Liu, Guanghua He

Abstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  5. Echoes from Intrinsic Connectivity Networks in the Subcortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
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  11. Review
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  13. Article
  14. Neurofunctional Segmentation Shifts in the Hippocampus.Frontiers in human neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hewei Cheng *Department of Biomedical Engineering, School of Bioinformatics, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China.
Hancan Zhu *College of Mathematics Physics and Information, Shaoxing University, Shaoxing, 312000, China.
Qiang Zheng *School of Computer and Control Engineering, Yantai University, Yantai, 264005, China.
Jie LiuResearch Institute of Education Development, Chongqing University of Posts and Telecommunications, Chongqing, 400065, China. jieliu218@163.com.
Guanghua HeCollege of International Finance and Trade, Zhejiang Yuexiu University of Foreign Languages, Shaoxing, 312000, China. hegh2003@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many unsupervised methods are widely used for parcellating the brain. However, unsupervised methods aren't able to integrate prior information, obtained from such as exiting functional neuroanatomy studies, to parcellate the brain, whereas the prior information guided semi-supervised method can generate more reliable brain parcellation. In this study, we propose a novel semi-supervised clustering method for parcellating the brain into spatially and functionally consistent parcels based on resting state functional magnetic resonance imaging (fMRI) data. Particularly, the prior supervised and spatial information is integrated into spectral clustering to achieve reliable brain parcellation. The proposed method has been validated in the hippocampus parcellation based on resting state fMRI data of 20 healthy adult subjects. The experimental results have demonstrated that the proposed method could successfully parcellate the hippocampus into head, body and tail parcels. The distinctive functional connectivity patterns of these parcels have further demonstrated the validity of the parcellation results. The effects of aging on the three hippocampus parcels' functional connectivity were also explored across the healthy adult subjects. Compared with state-of-the-art methods, the proposed method had better performance on functional homogeneity. Furthermore, the proposed method had good test-retest reproducibility validated by parcellating the hippocampus based on three repeated resting state fMRI scans from 24 healthy adult subjects.

Indexed as

AdolescentAdultAlgorithmsBrain MappingCluster AnalysisFemaleHippocampusHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedNeural PathwaysRestYoung Adult

Identifiers

PMID33009447
PMCPMC7532162

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.