ArticleNature communications2020
Disease trajectory browser for exploring temporal, population-wide disease progression patterns in 7.2 million Danish patients.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed.
- Data-driven identification of hub chains in disease accruals to reduce healthcare utilization and costs.Communications medicine · 2026Article
- Prediction of trajectories and outcomes in early-stage metabolic dysfunction-associated steatotic liver disease: a narrative review.EClinicalMedicine · 2026Review
- Scalable discovery and validation of order-specific electronic health record event trajectories for interpretable adverse-outcome risk estimation.Journal of biomedical informatics · 2026Article
- The role of artificial intelligence in advancing population-based cancer registration.Science bulletin · 2026Review
- Evaluation of trajectory analysis for disease risk assessment: a scoping review.Journal of the American Medical Informatics Association : JAMIA · 2026Article
- Automated generation of personalized trajectories of aging phenotypes with DyViA-GAN.Frontiers in aging · 2026Article
- Investigating multimorbidity trajectories in people living with MASLD diagnosis: A trajectory analysis using the UK Biobank.Diabetes, obesity & metabolism · 2025Article
- Disease clusters and death trajectories in individuals with frailty: a prospective cohort study from the UK Biobank.BMC public health · 2025Article
- Disease clusters and their genetic determinants following a diagnosis of depression: analyses based on a novel three-dimensional disease network approach.Molecular psychiatry · 2025Article
- Dynamics of multimorbidity patterns in older population across socioeconomic areas.Communications medicine · 2025Article
- Disease trajectory and mortality among sepsis patients: a prospective cohort study.BMC infectious diseases · 2025Article
- Comorbidity Disease Pattern in Japanese Elderly Population: A Network-Based Analysis.Mayo Clinic proceedings. Innovations, quality & outcomes · 2025Article
- Constructing the first comorbidity networks in companion dogs in the Dog Aging Project.PLoS computational biology · 2025Article
- Constructing the first comorbidity networks in companion dogs in the Dog Aging Project.bioRxiv : the preprint server for biology · 2025Article
- Temporal multimorbidity patterns and cluster identification: a longitudinal analysis of administrative data.BMC medicine · 2025Article
- Computational drug repurposing: approaches, evaluation of in silico resources and case studies.Nature reviews. Drug discovery · 2025Review
- Disease and mortality trajectories of cognitively able autistic individuals in mid- and later adulthood.BMC medicine · 2025Article
- Identifying and visualising temporal trajectories of hospitalisations for traditional and non-traditional complications in people with type 2 diabetes: a population-based study.The Lancet regional health. Western Pacific · 2025Article
- Digital twins as global learning health and disease models for preventive and personalized medicine.Genome medicine · 2025Review
- Comorbidity Networks From Population-Wide Health Data: Aggregated Data of 8.9M Hospital Patients (1997-2014).Scientific data · 2025Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We present the Danish Disease Trajectory Browser (DTB), a tool for exploring almost 25 years of data from the Danish National Patient Register. In the dataset comprising 7.2 million patients and 122 million admissions, users can identify diagnosis pairs with statistically significant directionality and combine them to linear disease trajectories. Users can search for one or more disease codes (ICD-10 classification) and explore disease progression patterns via an array of functionalities. For example, a set of linear trajectories can be merged into a disease trajectory network displaying the entire multimorbidity spectrum of a disease in a single connected graph. Using data from the Danish Register for Causes of Death mortality is also included. The tool is disease-agnostic across both rare and common diseases and is showcased by exploring multimorbidity in Down syndrome (ICD-10 code Q90) and hypertension (ICD-10 code I10). Finally, we show how search results can be customized and exported from the browser in a format of choice (i.e. JSON, PNG, JPEG and CSV).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.