Evidence map›Paper›PMID 33009099›Full record

ArticleCritical care medicine2020

Postdischarge Outcome Domains in Pediatric Critical Care and the Instruments Used to Evaluate Them: A Scoping Review.

Aline B Maddux, Neethi Pinto, Ericka L Fink, Mary E Hartman, Sholeen Nett, Katherine Biagas, Elizabeth Y Killien, Leslie A Dervan, LeeAnn M Christie, Peter M Luckett and 12 more

Open access · hybridAbstract readScoping Review
In one paragraph

Article in Critical care medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 1 pooled it
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 1 synthesis or guideline pooled it, 79 citations in OpenAlex.

  1. Neurocognitive functioning and health-related quality of life of children after pediatric intensive care admission: a systematic review.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
    Pooled it
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  4. Article
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  8. Eight PICU Follow-Up Programs in the United States Established From 2013 to 2022: Report From the Pediatric Outcomes Studies After PICU (POST-PICU) Investigators.Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
    Article
  9. Beyond Staying Alive….Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 7 institutions in 1 country.

Aline B MadduxDepartment of Pediatrics, Section of Critical Care Medicine, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
Neethi PintoDivision of Critical Care Medicine, Department of Anesthesiology and Critical Medicine, Children's Hospital of Philadelphia, Philadelphia, PA.
Ericka L FinkDepartment of Critical Care Medicine, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, PA.
Mary E HartmanDepartment of Pediatrics, Division of Critical Care Medicine, Washington University in St Louis, St. Louis, MO.
Sholeen NettDepartment of Pediatrics, Division of Pediatric Critical Care Medicine, Dartmouth-Hitchcock Medical Center, Children's Hospital at Dartmouth, Lebanon, NH.
Katherine BiagasDepartment of Pediatrics, Division of Critical Care Medicine, The Renaissance School of Medicine at Stony Brook University, Stony Brook, NY.
Elizabeth Y KillienPediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA.
Leslie A DervanPediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA.
LeeAnn M ChristieQuality management and Patient Safety, Dell Children's Medical Center, Austin, TX.
Peter M LuckettDepartment of Pediatrics, Division of Critical Care Medicine, University of Texas Southwestern Medical Center, Dallas, TX.
Laura LoftisDepartment of Pediatrics, Division of Critical Care Medicine, Baylor College of Medicine, Texas Children's Hospital, Houston, TX.
Mellanye LackeyHealth Sciences Library, University of Nevada, Las Vegas. Las Vegas, NV.
Melissa RingwoodDepartment of Pediatrics, Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT.
McKenna SmithDepartment of Pediatrics, Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Lenora OlsonDepartment of Pediatrics, Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Sam SorensonDepartment of Pediatrics, Critical Care Medicine, University of Utah School of Medicine, Salt Lake City, UT.
Kathleen L MeertDepartment of Pediatrics, Children's Hospital of Michigan, Detroit, MI.
Daniel A NottermanDepartment of Molecular Biology, Princeton, NJ.
Murray M PollackDepartment of Pediatrics, Children's National Health System, Washington, DC.
Peter M MouraniDepartment of Pediatrics, Section of Critical Care Medicine, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO.
R Scott WatsonPediatric Critical Care Medicine, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA.
Pediatric Outcomes STudies after PICU (POST-PICU) and PICU-COS Investigators of the Pediatric Acute Lung Injury and Sepsis Investigators and the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Networks
Children's Hospital Colorado · USSeattle Children's Hospital · USChildren's Hospital of Michigan · USChildren's National · USPrinceton University · USTexas Children's Hospital · USThe University of Texas Southwestern Medical Center · US

Funding

Data Coordinating Center for the Collaborative Pediatric Critical Care Research NetworkU01HD049934 · NICHD · UNIVERSITY OF UTAH · PI DEAN, JONATHAN MICHAEL · 2005 to 2020
$35.2M
Collaborative Pediatric Critical Care Research Network (CPCCRN) at Children's NationalUG1HD049981 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI POLLACK, MURRAY MICHAEL, WESSEL, DAVID LLOYD · 2015 to 2020
$1.8M
Renewal Application for the Childrens Hospital of Pittsburgh Collaborative Pediatric Critical Care Research Network SiteUG1HD049983 · NICHD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI CARCILLO, JOSEPH A · 2015 to 2020
$1.6M
Collaborative Pediatric Critical Care Research NetworkUG1HD050096 · NICHD · WAYNE STATE UNIVERSITY · PI MEERT, KATHLEEN L. · 2015 to 2020
$1.6M
Collaborative Network Study of Airway Microbiome and Host Responses in Pediatric Respiratory FailureUG1HD083171 · NICHD · UNIVERSITY OF COLORADO DENVER · PI CARPENTER, TODD C · 2015 to 2020
$1.5M
Collaborative Pediatric Critical Care Research Network - Clinical SiteRL1HD107773 · NICHD · CENTRAL MICHIGAN UNIVERSITY · PI KATHLEEN L. MEERT · 2021 to 2026
$862k
Functional Outcomes after Prolonged Mechanical Ventilation in ChildrenK23HD096018 · NICHD · UNIVERSITY OF COLORADO DENVER · PI MADDUX, ALINE BERNARD · 2019 to 2023
$807k
NHLBI NIH HHS L30 HL143674NICHD NIH HHS K23 HD096018NICHD NIH HHS RL1 HD107773NICHD NIH HHS U01 HD049934NICHD NIH HHS UG1 HD049981NICHD NIH HHS UG1 HD049983NICHD NIH HHS UG1 HD050096NICHD NIH HHS UG1 HD083171
6 · The paper itself

Abstract

objectivesAssessing outcomes after pediatric critical illness is imperative to evaluate practice and improve recovery of patients and their families. We conducted a scoping review of the literature to identify domains and instruments previously used to evaluate these outcomes.

designScoping review.

settingWe queried PubMed, EMBASE, PsycINFO, Cumulative Index of Nursing and Allied Health Literature, and the Cochrane Central Register of Controlled Trials Registry for studies evaluating pediatric critical care survivors or their families published between 1970 and 2017. We identified articles using key words related to pediatric critical illness and outcome domains. We excluded articles if the majority of patients were greater than 18 years old or less than 1 month old, mortality was the sole outcome, or only instrument psychometrics or procedural outcomes were reported. We used dual review for article selection and data extraction and categorized outcomes by domain (overall health, emotional, physical, cognitive, health-related quality of life, social, family). SUBJECTS: Manuscripts evaluating outcomes after pediatric critical illness.

interventionsNone. MEASUREMENTS AND MAIN

resultsOf 60,349 citations, 407 articles met inclusion criteria; 87% were published after 2000. Study designs included observational (85%), interventional (7%), qualitative (5%), and mixed methods (3%). Populations most frequently evaluated were traumatic brain injury (n = 96), general pediatric critical illness (n = 87), and congenital heart disease (n = 72). Family members were evaluated in 74 studies (18%). Studies used a median of 2 instruments (interquartile range 1-4 instruments) and evaluated a median of 2 domains (interquartile range 2-3 domains). Social (n = 223), cognitive (n = 183), and overall health (n = 161) domains were most frequently studied. Across studies, 366 unique instruments were used, most frequently the Wechsler and Glasgow Outcome Scales. Individual domains were evaluated using a median of 77 instruments (interquartile range 39-87 instruments).

conclusionsA comprehensive, generalizable understanding of outcomes after pediatric critical illness is limited by heterogeneity in methodology, populations, domains, and instruments. Developing assessment standards may improve understanding of postdischarge outcomes and support development of interventions after pediatric critical illness.

Indexed as

ChildCritical CareCritical IllnessHumansOutcome Assessment, Health CarePatient DischargeTreatment Outcome

Identifiers

PMID33009099
PMCPMC7708523
OpenAlexW3089846585

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.