Evidence map›Paper›PMID 33008937›Full record

ArticleThe European respiratory journal2021

Instability of sputum molecular phenotypes in U-BIOPRED severe asthma.

Nazanin Z Kermani, Stelios Pavlidis, Jiaxing Xie, Kai Sun, Matthew Loza, Fred Baribaud, Steve J Fowler, Dominic E Shaw, Louise J Fleming, Peter H Howarth and 11 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Asthma Pathogenesis: Phenotypes, Therapies, and Gaps: Summary of the Aspen Lung Conference 2023.American journal of respiratory cell and molecular biology · 2024
    Review
  9. Article
  10. Article
  11. Article
  12. Clinical Trial Design Innovations for Precision Medicine in Asthma.Advances in experimental medicine and biology · 2023
    Article
  13. Review
  14. Mechanisms of Mast Cell Activation in Severe Asthma: Beyond IgE.American journal of respiratory and critical care medicine · 2022
    Article
  15. Review
  16. Review
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors.

Nazanin Z KermaniDept of Computing and Data Science Institute, Imperial College London, London, UK.
Stelios PavlidisDept of Computing and Data Science Institute, Imperial College London, London, UK.
Jiaxing XieNational Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK.
Kai SunDept of Computing and Data Science Institute, Imperial College London, London, UK.
Matthew LozaJanssen Research and Development, High Wycombe, UK.
Fred BaribaudJanssen Research and Development, High Wycombe, UK.
Steve J FowlerCentre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester, UK.ORCID 0000-0002-4524-1663
Dominic E ShawRespiratory Research Unit, University of Nottingham, Nottingham, UK.ORCID 0000-0003-4106-8469
Louise J FlemingNational Heart and Lung Institute, Imperial College London, and Biomedical Research Unit, Royal Brompton and Harefield NHS Trust, London, UK.ORCID 0000-0002-7268-7433
Peter H HowarthNIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, Southampton, UK.
Ana R SousaRespiratory Therapeutic Unit, GSK, Stockley Park, UK.
Julie CorfieldAstraZeneca R&D, Molndal, Sweden.
Charles AuffrayEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France.
Bertrand De MeulderEuropean Institute for Systems Biology and Medicine, CNRS-ENS-UCBL-INSERM, Lyon, France.
Peter J SterkAmsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands.
Yike GuoDept of Computing and Data Science Institute, Imperial College London, London, UK.
Mohib UddinRespiratory Global Medicines Development, AstraZeneca, Gothenburg, Sweden.
Ratko DjukanovicNIHR Southampton Respiratory Biomedical Research Unit, Clinical and Experimental Sciences and Human Development and Health, Southampton, UK.
Ian M AdcockDept of Computing and Data Science Institute, Imperial College London, London, UK.ORCID 0000-0003-2101-8843
Kian Fan ChungDept of Computing and Data Science Institute, Imperial College London, London, UK.
U-BIOPRED study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaSputumEosinophilsHumansPhenotype

Identifiers

PMID33008937
PMCPMC7859503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.