Evidence map›Paper›PMID 33008833›Full record

ArticleCold Spring Harbor molecular case studies2020

Case report: 16-yr life history and genomic evolution of an ER

Bing Xu, Anu Amallraja, Padmapriya Swaminathan, Rachel Elsey, Christel Davis, Stephanie Theel, Sarah Viet, Jason Petersen, Amy Krie, Gareth Davies and 3 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Cold Spring Harbor molecular case studies, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Bing XuCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Anu AmallrajaCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Padmapriya SwaminathanCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Rachel ElseyCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Christel DavisAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Stephanie TheelAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Sarah VietAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Jason PetersenAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Amy KrieCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Gareth DaviesAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Casey B WilliamsCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Erik EhliAvera Institute for Human Genetics, Sioux Falls, South Dakota 57108, USA.
Tobias MeißnerCenter for Precision Oncology, Avera Cancer Institute, Sioux Falls, South Dakota 57105, USA.
Avera Health · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Metastatic breast cancer is one of the leading causes of cancer-related death in women. Limited studies have been done on the genomic evolution between primary and metastatic breast cancer. We reconstructed the genomic evolution through the 16-yr history of an ER

Indexed as

Evolution, MolecularGenomicsAromatase InhibitorsBreast NeoplasmsDNA Mutational AnalysisErb-b2 Receptor Tyrosine KinasesEstrogen Receptor alphaFemaleHumansMiddle AgedMutationPhosphatidylinositol 3-KinasesPhylogenySignal TransductionSOXB1 Transcription FactorsTranscriptomeAromatase InhibitorsERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesESR1 protein, humanEstrogen Receptor alphaPhosphatidylinositol 3-KinasesSOX2 protein, humanSOXB1 Transcription FactorsTFF1 protein, humanTrefoil Factor-1multifocal breast carcinoma

Identifiers

PMID33008833
PMCPMC7784492
OpenAlexW3090795443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.