Evidence map›Paper›PMID 33008821›Full record

ArticleApplied and environmental microbiology2020

Selection for Resistance to a Glyphosate-Containing Herbicide in Salmonella enterica Does Not Result in a Sustained Activation of the Tolerance Response or Increased Cross-Tolerance and Cross-Resistance to Clinically Important Antibiotics.

Judith Pöppe, Katrin Bote, Abhinaya Ramesh, Jayaseelan Murugaiyan, Benno Kuropka, Michael Kühl, Paul Johnston, Uwe Roesler, Olga Makarova

Open access · hybridAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Judith PöppeInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Katrin BoteInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Abhinaya RameshInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Jayaseelan MurugaiyanInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.ORCID 0000-0002-1924-2988
Benno KuropkaInstitute for Chemistry and Biochemistry, Freie Universität Berlin, Berlin, Germany.
Michael KühlInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Paul JohnstonEvolutionary Biology, Institute for Biology, Freie Universität Berlin, Berlin, Germany.
Uwe RoeslerInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany.
Olga MakarovaInstitute of Animal Hygiene and Environmental Health, Centre for Infection Medicine, Freie Universität Berlin, Berlin, Germany olga.makarova@fu-berlin.de.ORCID 0000-0003-4767-9711
Freie Universität Berlin · DELeibniz Institute of Freshwater Ecology and Inland Fisheries · DESRM University, Andhra Pradesh · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evolution of bacterial tolerance to antimicrobials precedes evolution of resistance and may result in cross-tolerance, cross-resistance, or collateral sensitivity to other antibiotics. Transient exposure of gut bacteria to glyphosate, the world's most widely used herbicide, has been linked to the activation of the stress response and changes in susceptibility to antibiotics. In this study, we investigated whether chronic exposure to a glyphosate-based herbicide (GBH) results in resistance, a constitutive activation of the tolerance and stress responses, and cross-tolerance or cross-resistance to antibiotics. Of the 10 farm animal-derived clinical isolates of

Indexed as

Selection, GeneticAnti-Bacterial AgentsDrug Resistance, BacterialGlycineGlyphosateHerbicide ResistanceHerbicidesSalmonella entericaAnti-Bacterial AgentsGlycineGlyphosateHerbicidesEnterobacteriaceaeexperimental evolutionfitness costsglyphosateresistancetolerance

Identifiers

PMID33008821
PMCPMC7688225
OpenAlexW3090024020

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.