Evidence map›Paper›PMID 33008393›Full record

ArticleBMC veterinary research2020

Disseminated Scedosporium apiospermum infection in a Maremmano-Abruzzese sheepdog.

Giovanni Di Teodoro, Daniela Averaimo, Miria Primavera, Doriana Santoleri, Giorgia Giovannini, Antonio Cocco, Gabriella Di Francesco, Daniela Malatesta, Sabrina Defourny, Nicola D'Alterio and 3 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC veterinary research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Medical mycology case reports · 2026
    Article
  2. Journal of fungi (Basel, Switzerland) · 2026
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Giovanni Di TeodoroIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy. g.diteodoro@izs.it.ORCID http://orcid.org/0000-0002-9595-782X
Daniela AveraimoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Miria PrimaveraClinica Veterinaria Guardiese, Via Anello, 66016, Guardiagrele, Chieti, Italy.
Doriana SantoleriClinica Veterinaria Guardiese, Via Anello, 66016, Guardiagrele, Chieti, Italy.
Giorgia GiovanniniClinica Veterinaria Guardiese, Via Anello, 66016, Guardiagrele, Chieti, Italy.
Antonio CoccoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Gabriella Di FrancescoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Daniela MalatestaIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Sabrina DefournyIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Nicola D'AlterioIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Valentina CuriniIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Marco Di DomenicoIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Antonio PetriniIstituto Zooprofilattico Sperimentale dell'Abruzzo e Molise "G. Caporale", Campo Boario, 64100, Teramo, Italy.
Istituto Zooprofilattico Sperimentale dell'Abruzzo e del Molise G. Caporale · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFew cases of scedosporiosis have been reported in animals, but the true prevalence is probably underestimated due to a lack of awareness. Scedosporiosis in dogs has often been associated with localized infection (i.e., nasal infection, eumycetoma, or keratomycosis) or, in rare cases, disseminated infections. CASE PRESENTATION: This case report describes the clinical and pathological features and the diagnostic process of a rare systemic and fatal fungal infection in a dog caused by Scedosporium apiospermum. A 10-month-old female Maremmano-Abruzzese sheepdog showing weakness, lethargy, lateral decubitus, miosis and muscular rigidity was presented. Rodenticide poisoning was clinically suspected for the differential diagnosis. However, postmortem examinations revealed the presence of a swollen and soft subcutaneous nodule located near the right inguinal breast, which was associated with massive enlargement of the inguinal lymph nodes and small disseminated, cream-colored nodules in the kidneys and mesentery. Multiple fungal pyogranulomas were observed upon histological examination. Fungal isolation from the kidneys, breast and inguinal lymph nodes was performed. The internal transcribed spacer (ITS) sequences from the fungal colony DNA were searched in BLAST in the NCBI GenBank for species identification. The sequences of the fungi isolated from the kidney and breast cultures showed 100% sequence identity with sequences from Scedosporium apiospermum.

conclusionsThis report shows that Scedosporium apiospermum may act as a primary pathogen in young and apparently healthy dogs and represents an important pathogen that should be considered during the diagnostic process, particularly when a fungal infection is suspected.

Indexed as

AnimalsDNA, FungalDog DiseasesDogsFemaleGranuloma, PyogenicInvasive Fungal InfectionsLymph NodesMycosesScedosporiumDNA, FungalCase reportDiagnosisDogScedosporium apiospermumSystemic mycosis

Identifiers

PMID33008393
PMCPMC7532623
OpenAlexW3091427365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.