Evidence map›Paper›PMID 33008130›Full record

ArticleAntibiotics (Basel, Switzerland)2020

From Orphan Phage to a Proposed New Family-the Diversity of N4-Like Viruses.

Johannes Wittmann, Dann Turner, Andrew D Millard, Padmanabhan Mahadevan, Andrew M Kropinski, Evelien M Adriaenssens

Abstract read
In one paragraph

Article in Antibiotics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Balancing of immune activation and suppression during phage infection.bioRxiv : the preprint server for biology · 2026
    Article
  5. Article
  6. Article
  7. An N4-likeJournal of bacteriology · 2026
    Article
  8. mBio · 2026
    Article
  9. Article
  10. Phage N4 uses a SAR endolysin-holin system for host cell lysis.bioRxiv : the preprint server for biology · 2025
    Article
  11. An N4-likebioRxiv : the preprint server for biology · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. [Basic knowledge of phages and their therapeutic application].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Moo19 and B2: Structures ofScience advances · 2024
    Article
  20. Successful phage-antibiotic therapy ofThe veterinary quarterly · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Johannes WittmannLeibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures, 38124 Braunschweig, Germany.
Dann TurnerDepartment of Applied Sciences, University of the West of England, Bristol BS16 1QY, UK.ORCID 0000-0002-0249-4513
Andrew D MillardDepartment of Genetics and Genome Biology, University of Leicester, Leicester LE1 7RH, UK.
Padmanabhan MahadevanDepartment of Biology, University of Tampa, Tampa, FL 33606, USA.
Andrew M KropinskiDepartment of Food Science, University of Guelph, Guelph, ON N1G 2W1, Canada.ORCID 0000-0002-6871-6799
Evelien M AdriaenssensQuadram Institute Bioscience, Norwich Research Park, Norwich NR4 7UQ, UK.ORCID 0000-0003-4826-5406

Funding

Biotechnology and Biological Sciences Research Council BBS/E/F/000PR10353Medical Research Council MR/L015080/1Medical Research Council MR/T030062/1
6 · The paper itself

Abstract

Escherichia phage N4 was isolated in 1966 in Italy and has remained a genomic orphan for a long time. It encodes an extremely large virion-associated RNA polymerase unique for bacterial viruses that became characteristic for this group. In recent years, due to new and relatively inexpensive sequencing techniques the number of publicly available phage genome sequences expanded rapidly. This revealed new members of the

Indexed as

bacterial virusesbacteriophagesICTVN4Schitoviridaevirus taxonomy

Identifiers

PMID33008130
PMCPMC7650795

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.