ReviewInternational journal of molecular sciences2020
Biomarkers Suggesting Favorable Prognostic Outcomes in Sudden Sensorineural Hearing Loss.
Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 57 citations in OpenAlex.
- Association Between Hematological Indices of Inflammation and Pathogenesis and Prognosis of Sudden Sensorineural Hearing Loss: A Systematic Review and Meta-Analysis.The journal of international advanced otology · 2025Pooled it
- Influential publications in sudden hearing loss: a bibliometric and visual synopsis of the top 100 cited articles.Frontiers in neurology · 2024Pooled it
- Digging into the Role of Inflammatory Biomarkers in Sudden Sensorineural Hearing Loss Diagnosis and Prognosis: A Systematic Review and Meta-Analysis.Medicina (Kaunas, Lithuania) · 2022Pooled it
- Study on the relationship between coagulation function, homocysteine, serum oxidative stress and sudden deafness and its clinical implications.Scientific reports · 2026Article
- A prognostic nomogram for all frequencies sudden sensorineural hearing loss based on the commixed index of inflammatory-immune-hemostasis-nutrition.Scientific reports · 2026Article
- Microcirculatory Dysfunction and Oxidative Stress in Sudden Sensorineural Hearing Loss: Insights From a Case-Control and Experimental Study.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- [Pathophysiologically complex bilateral profound sensorineural hearing loss in the setting of type 2 diabetes mellitus and fungal sepsis: a case report].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2026Article
- Hyperhomocysteinemia in sudden sensorineural hearing loss: Evidence from a prospective clinical study.PloS one · 2026Observational
- Neurovascular compression and vestibular compromises in idiopathic sudden sensorineural hearing loss.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Article
- Can inflammatory indices predict myringosclerosis?Saudi medical journal · 2025Article
- Dynamic Changes in Free Triiodothyronine (FT3) and Their Correlation with Hearing Recovery in Sudden Sensorineural Hearing Loss: Clinical Implications.Journal of otology · 2025Article
- Prognostic Factors and Clinical Characteristics in Pediatric Sudden Sensorineural Hearing Loss: A Retrospective Analysis.Laryngoscope investigative otolaryngology · 2025Article
- Chronic Inflammation and Hearing Loss: Key Biomarkers and Subgroup Differences by Gender and BMI in a National Cohort.Immunity, inflammation and disease · 2025Article
- [Research status and future strategies for refractory inner ear disease].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025Review
- Cognitive Disorders In Acquired Sensorineural Hearing Loss, At The Ent Department Of The "Village Bondeko" Center, In Kinshasa.Neuropsychiatric disease and treatment · 2025Article
- The Predictive Value of NLR, PLR and SII for SSNHL in Children and Young Adults.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- MicroRNAs as potential biomarkers for monitoring of acquired sensorineural hearing loss.Pediatric discovery · 2024Review
- Causal associations of white blood cell count and sudden sensorineural hearing loss: a bidirectional and multivariable Mendelian randomization study.Frontiers in neurology · 2024Article
- Clinical value of auditory nerve enhancement in idiopathic sudden sensorineural hearing loss: a retrospective study.Frontiers in neurology · 2024Article
- The Role of Fibrinogen, Homocysteine and Metabolic Syndrome's Alterations in Sudden Sensorineural Hearing Loss (SSHL): A Narrative Review.Medicina (Kaunas, Lithuania) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Sudden sensorineural hearing loss (SSNHL) is a medical emergency, making detailed examination to determine possible causes and early treatment important. However, etiological examinations in SSNHL do not always reveal a cause, and several factors have been found to affect treatment outcomes. Various studies are being performed to determine the prognosis and effects of treatment in patients who experience sudden hearing loss, and to identify biomarkers associated with this condition. Embase, PubMed, and the Cochrane database were searched using the key words SSNHL, prognostic, and biomarker. This search identified 4 articles in Embase, 28 articles in PubMed, and 36 in the Cochrane database. Of these 68 articles, 3 were duplicates and 37 were unrelated to the research topic. After excluding these articles, the remaining 28 articles were reviewed. Factors associated with SSNHL were divided into six categories: metabolic, hemostatic, inflammatory, immunologic, oxidative, and other factors. The associations between these factors with the occurrence of SSNHL and with patient prognosis were analyzed. Low monocyte counts, low neutrophil/lymphocyte ratio (NLR) and monocyte/high-density lipoproteins (HDL) cholesterol ratio (MHR), and low concentrations of fibrinogen, platelet glycoprotein (GP) IIIa, and TNF-α were found to be associated with good prognosis. However, these factors alone could not completely determine the onset of and recovery from SSNHL, suggesting the need for future basic and clinical studies.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.