Evidence map›Paper›PMID 33008089›Full record

ArticlePharmaceuticals (Basel, Switzerland)2020

Penetration into Cancer Cells via Clathrin-Dependent Mechanism Allows L-Asparaginase from

Anna A Plyasova, Marina V Pokrovskaya, Olga M Lisitsyna, Vadim S Pokrovsky, Svetlana S Alexandrova, Abdullah Hilal, Nikolay N Sokolov, Dmitry D Zhdanov

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
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  9. L-Lysine α-Oxidase: Enzyme with Anticancer Properties.Pharmaceuticals (Basel, Switzerland) · 2021
    Review
  10. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Anna A PlyasovaInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Marina V PokrovskayaInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Olga M LisitsynaInternational Biotechnology Center "Generium" LLC, Vladimirskaya st. 14, 601125 Volginsky, Russia.
Vadim S PokrovskyN.N. Blokhin Cancer Research Center, Kashirskoe Shosse 24, 115478 Moscow, Russia.
Svetlana S AlexandrovaInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Abdullah HilalInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Nikolay N SokolovInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Dmitry D ZhdanovInstitute of Biomedical Chemistry, Pogodinskaya st. 10/8, 119121 Moscow, Russia.
Institute of Biomedical Chemistry · RUPeoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anticancer effect of L-asparaginases (L-ASNases) is attributable to their ability to hydrolyze L-asparagine in the bloodstream and cancer cell microenvironment.

Indexed as

clathrindynaminendocytosisRhodospirillum rubrum L-asparaginasetelomerase

Identifiers

PMID33008089
PMCPMC7650658
OpenAlexW3090499067

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.