ArticleMaterials (Basel, Switzerland)2020
PlantCrystals-Nanosized Plant Material for Improved Bioefficacy of Medical Plants.
Article in Materials (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- High Flavonoid Content inPharmaceutical nanotechnology · 2026Article
- Silymarin PlantCrystals for Improved Dermal Drug Delivery.Bioengineering (Basel, Switzerland) · 2025Article
- Nano-PhotoCrystals (Photosensitive Nanocrystals) of Aloe Emodin Combined with Dissolving Microneedles for Dual Smart Targeting of Acute Bacterial Skin and Soft Tissue Infections.ACS applied materials & interfaces · 2025Article
- Challenges, Unmet Needs, and Future Directions for Nanocrystals in Dermal Drug Delivery.Molecules (Basel, Switzerland) · 2025Review
- Extracellular Vesicles and PlantCrystals for Improved Bioavailability of Curcumin as a BCS Class IV Drug.Molecules (Basel, Switzerland) · 2024Article
- Assessing the Oxidative State of the Skin by Combining Classical Tape Stripping with ORAC Assay.Pharmaceuticals (Basel, Switzerland) · 2022Article
- Assessing the Dermal Penetration Efficacy of Chemical Compounds with the Ex-Vivo Porcine Ear Model.Pharmaceutics · 2022Article
- Cucumber-Derived Exosome-like Vesicles and PlantCrystals for Improved Dermal Drug Delivery.Pharmaceutics · 2022Article
- Production and Characterization of Sumac PlantCrystals: Influence of High-Pressure Homogenization on Antioxidant Activity of Sumac (Plants (Basel, Switzerland) · 2021Article
- Unleashing the Biological Potential ofAntioxidants (Basel, Switzerland) · 2021Article
- Improved Antioxidant Capacity of Black Tea Waste Utilizing PlantCrystals.Molecules (Basel, Switzerland) · 2021Article
- Inhibition of mast cell activation via MRGPRX2 receptor byAvicenna journal of phytomedicineArticle
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PlantCrystals are obtained by milling plant material to sizes <10 µm. Due to the disruption of the plant cells, active compounds are easily released, rendering the PlantCrystal technology an effective and low-cost process for the production of environmentally friendly plant extracts. The extracts can be used to produce phytomedicines, nutritional supplements or cosmetic products. Previous studies could already demonstrate the use of PlantCrystals to improve the antimicrobial or antifungal activity of different plants. This study investigated whether PlantCrystal technology is suitable to produce plant derived formulations with high antioxidant capacity. The study also aimed to identify the most suitable production methods for this.
methodsVarious plant materials and parts of plants, i.e., seeds, leaves and flowers, and different methods were employed for the production. PlantCrystals were characterized regarding size, physical stability and antioxidant capacity (AOC).
resultsPlantCrystals with particles <1 µm were produced from the different plant materials. Both production methods, i.e., high-pressure homogenization, bead milling or the combination of both were suitable to obtain PlantCrystals. Nano milling of the plant material greatly affected their AOC and resulted in formulations with distinctly higher AOC when compared to classical extracts.
conclusionsRendering plant material into small sized particles is highly effective to obtain plant extracts with high biological efficacy.
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