Evidence map›Paper›PMID 33008057›Full record

ReviewNutrients2020

Very Long Chain Marine

Harald Arnesen, Peder L Myhre, Ingebjørg Seljeflot

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
  3. Marine Natural Products and Coronary Artery Disease.Frontiers in cardiovascular medicine · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Harald ArnesenCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Pb 4956 Nydalen, 0424 Oslo, Norway.
Peder L MyhreFaculty of Medicine, University of Oslo, 0424 Oslo, Norway.
Ingebjørg SeljeflotCenter for Clinical Heart Research, Department of Cardiology, Oslo University Hospital Ullevål, Pb 4956 Nydalen, 0424 Oslo, Norway.ORCID 0000-0003-4071-3358
Oslo University Hospital · NOUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The global burden of atherothrombotic heart disease should be considered as a life-style disorder where differences in dietary habits and related risk factors like limited physical activity and adiposity together play important roles. Related metabolic changes have been scientifically elucidated in recent decades, and the role of the very-long-chain marine fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) have been much focused on, especially their possible effects on processes like inflammation and thrombosis. In the present brief review of related metabolic mechanisms, the effects of these fatty acids in a clinical setting have been referred to, including some of the authors' work on this topic. The main focus is the divergent results in the field and the important differences between the study population, the type of supplements and fresh marine sources, the proportion of EPA versus DHA dosages, and the duration of supplementation in clinical trials. We conclude that daily intake of at least 1 g of EPA + DHA may improve a dysmetabolic state in the population. The potential to reduce the risk and progression of atherothrombotic heart disease is still a matter of debate.

Indexed as

Dietary SupplementsClinical Trials as TopicCoronary Artery DiseaseCoronary ThrombosisDiet, HealthyDocosahexaenoic AcidsEatingEicosapentaenoic AcidFatty Acids, Omega-3Heart Disease Risk FactorsHeart DiseasesHumansSeafoodDocosahexaenoic AcidsEicosapentaenoic AcidFatty Acids, Omega-3atherothrombosisclinical trialsinflammationmetabolismomega-3 fatty acids

Identifiers

PMID33008057
PMCPMC7601282
OpenAlexW3091279574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.