Evidence map›Paper›PMID 33008043›Full record

ArticleToxins2020

Management of Anterocapitis and Anterocollis: A Novel Ultrasound Guided Approach Combined with Electromyography for Botulinum Toxin Injection of Longus Colli and Longus Capitis.

Michael Farrell, Barbara I Karp, Panagiotis Kassavetis, William Berrigan, Simge Yonter, Debra Ehrlich, Katharine E Alter

Open access · goldAbstract readVideo-Audio Media
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Localization modalities for botulinum neurotoxin injection.Toxicon : official journal of the International Society on Toxinology · 2025
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Michael FarrellMedStar/Georgetown University National Rehabilitation Hospital, Washington, DC 20010, USA.ORCID 0000-0002-0357-8233
Barbara I KarpNational Institutes of Neurological Disorders and Stroke, Bethesda, MD, 20892 USA.
Panagiotis KassavetisNational Institutes of Neurological Disorders and Stroke, Bethesda, MD, 20892 USA.
William BerriganEmory School of Medicine, Emory University, Atlanta, GA 30322, USA.ORCID 0000-0002-0480-2372
Simge YonterRehabilitation Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892-1604, USA.
Debra EhrlichNational Institutes of Neurological Disorders and Stroke, Bethesda, MD, 20892 USA.
Katharine E AlterFunctional and Applied Biomechanics Section, Rehabilitation Medicine, Clinical Center, National Institutes of Health, Bethesda, MD 20892-1604, USA.ORCID 0000-0002-5405-2143
National Institute of Neurological Disorders and Stroke · USNational Institutes of Health Clinical Center · USEmory University · USMedStar National Rehabilitation Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemodenervation of cervical musculature using botulinum neurotoxin (BoNT) is established as the gold standard or treatment of choice for management of Cervical Dystonia (CD). The success of BoNT procedures is measured by improved symptomology while minimizing side effects and is dependent upon many factors including: clinical pattern recognition, identifying contributory muscles, BoNT dosage, and locating and safely injecting target muscles. In patients with CD, treatment of anterocollis (forward flexion of the neck) and anterocaput (anterocapitis) (forward flexion of the head) are inarguably challenging. The longus Colli (LoCol) and longus capitis (LoCap) muscles, two deep cervical spine and head flexor muscles, frequently contribute to these patterns. Localizing and safely injecting these muscles is particularly challenging owing to their deep location and the complex regional anatomy which includes critical neurovascular and other structures. Ultrasound (US) guidance provides direct visualization of the LoCol, LoCap, other cervical muscles and adjacent structures reducing the risks and side effects while improving the clinical outcome of BoNT for these conditions. The addition of electromyography (EMG) provides confirmation of muscle activity within the target muscle. Within this manuscript, we present a technical description of a novel US guided approach (combined with EMG) for BoNT injection into the LoCol and LoCap muscles for the management of anterocollis and anterocaput in patients with CD.

Indexed as

ElectromyographyUltrasonography, InterventionalAcetylcholine Release InhibitorsAnatomic LandmarksBotulinum ToxinsHumansInjections, IntramuscularNeck MusclesPatient PositioningPredictive Value of TestsTorticollisTreatment OutcomeAcetylcholine Release InhibitorsBotulinum Toxinsanterocaputanterocollisbotulinum toxinscervical dystoniachemodenervationhead and neckinjection techniquelongus capitislongus colliultrasound guidance

Identifiers

PMID33008043
PMCPMC7650774
OpenAlexW3089763836

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.