Evidence map›Paper›PMID 33008024›Full record

ArticleCancers2020

Biopathological Significance of PIWI-piRNA Pathway Deregulation in Invasive Breast Carcinomas.

Didier Meseure, Sophie Vacher, Sabah Boudjemaa, Marick Laé, André Nicolas, Renaud Leclere, Walid Chemlali, Gabriel Champenois, Anne Schnitzler, Laetitia Lesage and 2 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Didier MeseureUnit of Pharmacogenomics, Department of Genetics, Institut Curie, 75005 Paris, France.
Sophie VacherUnit of Pharmacogenomics, Department of Genetics, Institut Curie, 75005 Paris, France.ORCID 0000-0002-0042-6023
Sabah BoudjemaaDepartment of Pathology, Hôpital Armand Trousseau, 75012 Paris, France.
Marick LaéDepartment of Pathology, Centre Henri Becquerel, INSERM U1245 UniRouen Normandie Université, rue d'Amiens, 76000 Rouen, France.
André NicolasPlatform of Experimental Pathology PATHEX, Institut Curie, 75005 Paris, France.
Renaud LeclerePlatform of Experimental Pathology PATHEX, Institut Curie, 75005 Paris, France.
Walid ChemlaliUnit of Pharmacogenomics, Department of Genetics, Institut Curie, 75005 Paris, France.
Gabriel ChampenoisPlatform of Experimental Pathology PATHEX, Institut Curie, 75005 Paris, France.
Anne SchnitzlerUnit of Pharmacogenomics, Department of Genetics, Institut Curie, 75005 Paris, France.
Laetitia LesagePlatform of Experimental Pathology PATHEX, Institut Curie, 75005 Paris, France.
Thierry DuboisBreast Cancer Biology Group, Translational Research Department, Institut Curie, Université PSL, 75005 Paris, France.ORCID 0000-0003-4739-6164
Ivan BiecheUnit of Pharmacogenomics, Department of Genetics, Institut Curie, 75005 Paris, France.
Institut Curie · FRDélégation Paris 5 · FRInserm · FRSorbonne Université · FRUniversité Paris Sciences et Lettres · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The PIWI proteins emerging in the development of human cancers, edify PIWI-piRNA ribonucleoproteic complexes acting as pivotal regulators of genome integrity, differentiation and homeostasis. The aim of this study is to analyze the four PIWILs gene expression in invasive breast carcinomas (IBCs): at RNA level using quantitative RT-PCR (

Indexed as

breast carcinomasheterochromatinmethylationpiRNAPIWI proteinssilencingtransposable elements

Identifiers

PMID33008024
PMCPMC7600338
OpenAlexW3089707642

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.