Evidence map›Paper›PMID 33007869›Full record

ArticleCancers2020

Inflammatory Breast Cancer: Clinical Implications of Genomic Alterations and Mutational Profiling.

Flávia L C Faldoni, Rolando A R Villacis, Luisa M Canto, Carlos E Fonseca-Alves, Sarah S Cury, Simon J Larsen, Mads M Aagaard, Cristiano P Souza, Cristovam Scapulatempo-Neto, Cynthia A B T Osório and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

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  12. American journal of cancer research · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 3 countries.

Flávia L C FaldoniInternational Research Center, A.C.Camargo Cancer Center, São Paulo 01508-010, Brazil.
Rolando A R VillacisDepartment of Genetics and Morphology, Institute of Biological Sciences, University of Brasília-UnB, Brasília 70910-900, Brazil.ORCID 0000-0003-3851-2696
Luisa M CantoDepartment of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0001-9095-9431
Carlos E Fonseca-AlvesDepartment of Veterinary Surgery and Anesthesiology, School of Veterinary Medicine and Animal Science, São Paulo State University-UNESP, Botucatu 18618-681, Brazil.ORCID 0000-0002-6702-6139
Sarah S CuryDepartment of Structural and Functional Biology, Institute of Biosciences, São Paulo State University-UNESP, Botucatu 18618-689, Brazil.
Simon J LarsenDepartment of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark.ORCID 0000-0001-8076-5035
Mads M AagaardDepartment of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark.ORCID 0000-0003-4742-7047
Cristiano P SouzaDepartment of Breast and Gynecologic Oncology, Barretos Cancer Hospital, Pio XII Foundation, Barretos 14784-390, Brazil.
Cristovam Scapulatempo-NetoMolecular Oncology Research Center, Barretos, SP, 14784-400, and Diagnósticos da América (DASA), Barueri 01525-001, Brazil.
Cynthia A B T OsórioDepartment of Pathology, A.C.Camargo Cancer Center, São Paulo 01525-001, Brazil.
Jan BaumbachDepartment of Mathematics and Computer Science, University of Southern Denmark, 5230 Odense, Denmark.
Fabio A MarchiInternational Research Center, A.C.Camargo Cancer Center, São Paulo 01508-010, Brazil.ORCID 0000-0001-5815-8423
Silvia R RogattoDepartment of Clinical Genetics, University Hospital of Southern Denmark, 7100 Vejle, Denmark.
AC Camargo Hospital · BRUniversity of Southern Denmark · DKHospital de Câncer de Barretos · BRUniversidade Estadual Paulista (Unesp) · BRUniversidade de Brasília · BR

Funding

Region of Southern Denmark Research Fund NoneUniversity Hospital of Southern Denmark None
6 · The paper itself

Abstract

Inflammatory breast cancer (IBC) is a rare and aggressive type of breast cancer whose molecular basis is poorly understood. We performed a comprehensive molecular analysis of 24 IBC biopsies naïve of treatment, using a high-resolution microarray platform and targeted next-generation sequencing (105 cancer-related genes). The genes more frequently affected by gains were

Indexed as

copy number alterationsgene variantsgenomic scarshomologous recombination deficiencyinflammatory breast cancermicroarray

Identifiers

PMID33007869
PMCPMC7650681
OpenAlexW3091070974

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.