Evidence map›Paper›PMID 33007868›Full record

ArticleNutrients2020

Cord Blood Levels of EPA, a Marker of Fish Intake, Correlate with Infants' T- and B-Lymphocyte Phenotypes and Risk for Allergic Disease.

Malin Barman, Hardis Rabe, Bill Hesselmar, Susanne Johansen, Ann-Sofie Sandberg, Agnes E Wold

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Associations between maternal fish intake and polyunsaturated fatty acid status with childhood asthma in a high fish-eating population.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Malin BarmanFood and Nutrition Science, Department of Biology and Biological Engineering, Chalmers, University of Technology, 41296 Göteborg, Sweden.ORCID 0000-0002-5317-2768
Hardis RabeInstitute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, 40530 Göteborg, Sweden.ORCID 0000-0003-1184-6135
Bill HesselmarDepartment of Pediatrics, Institute of Clinical Sciences, The Sahlgrenska Academy, University of Gothenburg, 40530 Göteborg, Sweden.
Susanne JohansenPediatric Clinic, Skaraborg Hospital, 53151 Lidköping, Sweden.
Ann-Sofie SandbergFood and Nutrition Science, Department of Biology and Biological Engineering, Chalmers, University of Technology, 41296 Göteborg, Sweden.ORCID 0000-0002-9681-3342
Agnes E WoldInstitute of Biomedicine, Department of Infectious Diseases, University of Gothenburg, 40530 Göteborg, Sweden.
University of Gothenburg · SEChalmers University of Technology · SESkaraborg Hospital · SE

Funding

Svenska Forskningsrådet Formas 222-2004-1958Vetenskapsrådet 2019-01317Vetenskapsrådet 521-2013-3154
6 · The paper itself

Abstract

Maternal fish intake during pregnancy has been associated with reduced allergy development in the offspring and here, we hypothesized that components of fish stimulate fetal immune maturation. The aim of this study was to investigate how maternal fish intake during pregnancy and levels of n-3 long-chain polyunsaturated fatty acids (LCPUFAs) in the infant's cord serum correlated with different subsets of B- and T-cells in cord blood and B-cell activating factor (BAFF) in cord plasma, and with doctor-diagnosed allergy at 3 and 8 years of age in the FARMFLORA birth-cohort consisting of 65 families. Principal component analysis showed that infant allergies at 3 or 8 years of age were negatively associated with the proportions of n-3 LCPUFAs (eicosapentaenoic acid, docosapentaenoic acid, and docosahexaenoic acid) in infant cord serum, which, in turn correlated positively with maternal fish intake during pregnancy. Both maternal fish intake and cord serum n-3 LCPUFAs correlated negatively to CD5

Indexed as

AdultAnimalsB-Cell Activating FactorBiomarkersB-LymphocytesChildChild, PreschoolFatty Acids, Omega-3FemaleFetal BloodFishesHumansHypersensitivityInfantInfant, NewbornMaleB-Cell Activating FactorBiomarkersFatty Acids, Omega-3allergyB celleicosapentaenoic acidfarmingfatty acidsfishn-3 LCPUFAregulatory T cellsT cells

Identifiers

PMID33007868
PMCPMC7601506
OpenAlexW3091758888

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.