Evidence map›Paper›PMID 33007778›Full record

ArticleNeuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2021

Multimodal investigation of dopamine D

Patrick D Worhunsky, Gustavo A Angarita, Zu Wei Zhai, David Matuskey, Jean-Dominique Gallezot, Robert T Malison, Richard E Carson, Marc N Potenza

Open access · bronzeAbstract read
In one paragraph

Article in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Independent component analysis for internet gaming disorder.Dialogues in clinical neuroscience · 2023
    Review
  8. Article
  9. Review
  10. Behavioral Inflexibility from a Neuronal Population Perspective.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Patrick D WorhunskyDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA. patrick.worhunsky@yale.edu.ORCID http://orcid.org/0000-0001-9629-1428
Gustavo A AngaritaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Zu Wei ZhaiDepartment of Psychology, Middlebury College, Middlebury, VT, USA.
David MatuskeyDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0001-7508-6572
Jean-Dominique GallezotDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0003-0399-8374
Robert T MalisonDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Richard E CarsonDepartment of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-9338-7966
Marc N PotenzaDepartment of Psychiatry, Yale School of Medicine, New Haven, CT, USA.
Yale University · USMiddlebury College · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Translational Research of Cocaine, Striatum, and ImpulsivitiesP20DA027844 · NIDA · YALE UNIVERSITY · PI TAYLOR, JANE R · 2010 to 2013
$3.6M
Investigation of neurofunctional reorganization in cocaine addiction using mGluR5 PET and fMRIK01DA042998 · NIDA · YALE UNIVERSITY · PI WORHUNSKY, PATRICK D · 2017 to 2021
$900k
Functional networks related to cocaine dependence and its treatment and relapseR01DA039136 · NIDA · YALE UNIVERSITY · PI POTENZA, MARC N · 2016 to 2018
$754k
DBH, D2High and Cocaine Paranoia/Aversion: A [11C]PHNO PET StudyR03DA027456 · NIDA · YALE UNIVERSITY · PI MALISON, ROBERT T · 2009 to 2010
$420k
NCATS NIH HHS UL1 TR000142NCATS NIH HHS UL1 TR001863NIDA NIH HHS K01 DA042998NIDA NIH HHS P20 DA027844NIDA NIH HHS R01 DA039136NIDA NIH HHS R03 DA027456
6 · The paper itself

Abstract

Stimulant-use disorders have been associated with lower availability of dopamine type-2 receptors (D2R) and greater availability of type-3 receptors (D3R). Links between D2R levels, cognitive performance, and suppression of the default mode network (DMN) during executive functioning have been observed in healthy and addicted populations; however, there is limited evidence regarding a potential role of elevated D3R in influencing cognitive control processes in groups with and without addictions. Sixteen individuals with cocaine-use disorder (CUD) and 16 healthy comparison (HC) participants completed [

Indexed as

CocaineDopamineCognitionDefault Mode NetworkHumansReceptors, Dopamine D2Receptors, Dopamine D3CocaineDopamineReceptors, Dopamine D2Receptors, Dopamine D3

Identifiers

PMID33007778
PMCPMC7852666
OpenAlexW3091199951

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.