Evidence map›Paper›PMID 33007716›Full record

ArticleTheriogenology2020

Ascorbic acid promotes the reproductive function of porcine immature Sertoli cells through transcriptome reprogramming.

Yu-Wei Yang, Lu Chen, Qiao Mou, Hao Liang, Zhi-Qiang Du, Cai-Xia Yang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Theriogenology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Epigenetic regulations in mammalian spermatogenesis: RNA-mCellular and molecular life sciences : CMLS · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yu-Wei YangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China.
Lu ChenCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China.
Qiao MouCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China.
Hao LiangCollege of Animal Science, Yangtze University, Jingzhou, 434025, Hubei, China.
Zhi-Qiang DuCollege of Animal Science, Yangtze University, Jingzhou, 434025, Hubei, China. Electronic address: zhqdu@yangtzeu.edu.cn.
Cai-Xia YangCollege of Animal Science and Technology, Northeast Agricultural University, Harbin, 150030, Heilongjiang, China; College of Animal Science, Yangtze University, Jingzhou, 434025, Hubei, China. Electronic address: caixiayang@neau.edu.cn.
Northeast Agricultural University · CNYangtze University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vitamin C (ascorbic acid, AA) can regulate antioxidation and affect many cellular processes. However, the effect of AA on the reproduction of male animals remains less explored. Here, we showed that by supplementing exogenous AA to porcine immature Sertoli cells (iSCs), AA could promote the proliferation, suppress apoptosis, and decrease the global nucleic acid methylation (5 mC and m

Indexed as

RNA, Long NoncodingTranscriptomeAnimalsAscorbic AcidGene Expression ProfilingMaleRNA, MessengerSertoli CellsSwineAscorbic AcidRNA, Long NoncodingRNA, MessengerAscorbic acidHormoneImmature Sertoli cellMetabolitePigTranscriptome

Identifiers

PMID33007716
PMCPMC7524525
OpenAlexW3091027170

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.