Evidence map›Paper›PMID 33007461›Full record

ReviewNeurobiology of learning and memory2020

Generalization and the hippocampus: More than one story?

Dagmar Zeithamova, Caitlin R Bowman

Abstract readReview
In one paragraph

Review in Neurobiology of learning and memory, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Foundational Number Sense Training Gains Are Predicted by Hippocampal-Parietal Circuits.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Pooled it
  3. Article
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  8. Distinct contributions of hippocampal pathways in learning regularities and exceptions revealed by functional footprints.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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  15. Thinking as Analogy-Making: Toward a Neural Process Account of General Intelligence.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025
    Review
  16. Article
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  18. Neural Activity Differentiates Novel and Learned Event Boundaries.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dagmar ZeithamovaUniversity of Oregon, United States. Electronic address: dasa@uoregon.edu.
Caitlin R BowmanUniversity of Oregon, United States; University of Wisconsin-Milwaukee, United States.

Funding

Neural mechanisms of specificity and generalization learningR01NS112366 · NINDS · UNIVERSITY OF OREGON · PI ZEITHAMOVA, DAGMAR · 2020 to 2024
$1.7M
Memory precision and generalization: aging effects on the cognitive and neural basis of adaptive memory functionF32AG054204 · NIA · UNIVERSITY OF OREGON · PI BOWMAN, CAITLIN R. · 2017 to 2019
$179k
NIA NIH HHS F32 AG054204NINDS NIH HHS R01 NS112366
6 · The paper itself

Abstract

Memory-based cognition depends on both the ability to remember specific details of individual experiences and the ability to combine information across experiences to generalize and derive new knowledge. A hippocampal role in rapid encoding of specific events is long established. More recent research also demonstrates hippocampal contributions to generalization, but their nature is still debated. The current review provides an overview of hippocampal-based generalization in two lines of research-episodic inference and categorization-and discusses evidence for four candidate mechanisms and representational schemes that may underpin such generalization. We highlight evidence showing that the hippocampus contributes specific memories to generalization decisions, but also forms generalized representations that integrate information across experiences. Multiple views are currently plausible of how such generalized representations form and relate to specific memories. Future research that uses behavioral and neural indices of both generalization and specificity may help resolve between the candidate generalization mechanisms, with the possibility that more than one view of hippocampal-based generalization may be valid. Importantly, all views share the emphasis on the broader role of the hippocampus in cognition that goes beyond remembering the past.

Indexed as

Concept FormationGeneralization, PsychologicalHippocampusHumansMemoryCategorizationConcept learningEpisodic memoryHippocampusInferenceMemory integration

Identifiers

PMID33007461
PMCPMC7655622

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.