Evidence map›Paper›PMID 33007400›Full record

ReviewMedecine et maladies infectieuses2020

COVID-19 in clinical practice: A narrative synthesis.

M Le Maréchal, P Morand, O Epaulard, B Némoz

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in Medecine et maladies infectieuses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04654442 (Evaluation of the Feasibility and Analytic Performance of TestNPass), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 48% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04654442 completednot on this mapstarted 2021, after this paper: background citation

Evaluation of the Feasibility and Analytic Performance of TestNPass (In Vitro Diagnosis Medical Device) for CoViD-19 Diagnosis on Saliva Sample. : a Pilot Study

TypeobservationalSponsorUniversity Hospital, GrenobleRan2021 to 2021Enrolled60ConditionsCovid19, SARS-CoV-2ArmsTestNPass
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

M Le MaréchalService de Maladies Infectieuses, CHU de Grenoble-Alpes, France. Electronic address: mlemarechal@chu-grenoble.fr.
P MorandLaboratoire de Virologie, Institut de Biologie et de Pathologie, CHU de Grenoble-Alpes, France.
O EpaulardService de Maladies Infectieuses, CHU de Grenoble-Alpes, France.
B NémozLaboratoire de Virologie, Institut de Biologie et de Pathologie, CHU de Grenoble-Alpes, France.
Centre Hospitalier Universitaire de Grenoble · FRInstitut de Virologie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The coronavirus disease 2019 (COVID-19) was first reported in the city of Wuhan, China. The disease rapidly spread to the rest of China, to Southern-East Asia, then to Europe, America, and on to the rest of the world. COVID-19 is associated with a betacoronavirus named SARS-CoV-2. The virus penetrates the organism through the respiratory tract, conveyed by contaminated droplets. The main cell receptor targeted is the surface-bound ACE-2. As of the 26th July 2020, 15,200,000 COVID-19 cases and 650,000 deaths were reported worldwide. The mortality rate is estimated between 1.3 and 18.3%. The reproductive rate without any public health intervention is estimated around 4-5.1 in France. Most hospitalized patients for COVID-19 present respiratory symptoms, which in some cases is associated with fever. Up to 86% of admissions to ICU are related to acute respiratory failure. To date, no anti-viral therapy has proven its efficacy considering randomized trials. Only immunomodulatory treatments such as corticosteroids have shown to cause significant improvement in patient outcome.

Indexed as

PandemicsPractice Patterns, Physicians'Antiviral AgentsBetacoronavirusChinaCoronavirus InfectionsCOVID-19COVID-19 Drug TreatmentEuropeFranceHumansMortalityPneumonia, ViralRandomized Controlled Trials as TopicSARS-CoV-2Antiviral AgentsCOVID-19

Identifiers

PMID33007400
PMCPMC7524428
OpenAlexW3088123964

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.