Evidence map›Paper›PMID 33007384›Full record

ArticleToxicology and applied pharmacology2020

Biological effects of inhaled hydraulic fracturing sand dust. VIII. Immunotoxicity.

Stacey E Anderson, Hillary Shane, Carrie Long, Antonella Marrocco, Ewa Lukomska, Jenny R Roberts, Nikki Marshall, Jeffrey S Fedan

Open access · greenAbstract read
In one paragraph

Article in Toxicology and applied pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Stacey E AndersonHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America. Electronic address: sanderson4@cdc.gov.
Hillary ShaneHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Carrie LongHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Antonella MarroccoHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Ewa LukomskaHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Jenny R RobertsHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Nikki MarshallHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
Jeffrey S FedanHealth Effects Laboratory Division, National Institute for Occupational Safety and Health, Morgantown, WV 26505, United States of America.
National Institute for Occupational Safety and Health · US

Funding

West Virginia IDEA-CTRU54GM104942 · NIGMS · WEST VIRGINIA UNIVERSITY · PI Laura F. Gibson · 2012 to 2026
$81.0M
Intramural CDC HHS CC999999NIGMS NIH HHS U54 GM104942
6 · The paper itself

Abstract

Hydraulic fracturing ("fracking") is a process used to enhance retrieval of gas from subterranean natural gas-laden rock by fracturing it under pressure. Sand used to stabilize fissures and facilitate gas flow creates a potential occupational hazard from respirable fracking sand dust (FSD). As studies of the immunotoxicity of FSD are lacking, the effects of whole-body inhalation (6 h/d for 4 d) of a FSD, i.e., FSD 8, was investigated at 1, 7, and 27 d post-exposure in rats. Exposure to 10 mg/m

Indexed as

DustHydraulic FrackingSandAdministration, InhalationAnimalsBronchoalveolar Lavage FluidCD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCell LineErythrocytesImmunoglobulin MKiller Cells, NaturalLymph NodesMaleMiceRats, Sprague-DawleyDustImmunoglobulin MSandFrackingFracking sand dustImmune phenotypingImmunosuppressionImmunotoxicity

Identifiers

PMID33007384
PMCPMC7796771
OpenAlexW3090009184

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.