Evidence map›Paper›PMID 33007198›Full record

ArticleAmerican journal of human genetics2020

Roadmap for Establishing Large-Scale Genomic Medicine Initiatives in Low- and Middle-Income Countries.

George P Patrinos, Emmanouil Pasparakis, Erasmia Koiliari, Alexandre C Pereira, Tábita Hünemeier, Lygia V Pereira, Christina Mitropoulou

Open access · bronzeAbstract read
In one paragraph

Article in American journal of human genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  5. Egypt Genome: Towards an African new genomic era.Journal of advanced research · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 4 countries.

George P PatrinosUniversity of Patras School of Health Sciences, Department of Pharmacy, Patras 265 04, Greece; United Arab Emirates University, College of Medicine and Health Sciences, Department of Pathology, Al-Ain, UAE; United Arab Emirates University, Zayed Center of Health Sciences, Al-Ain, UAE. Electronic address: gpatrinos@upatras.gr.
Emmanouil PasparakisMedical Center of Crete, Irakleion, 700 03, Greece.
Erasmia KoiliariMedical Center of Crete, Irakleion, 700 03, Greece.
Alexandre C PereiraLaboratory of Genetics and Molecular Cardiology, Heart Institute, University of Sao Paulo Medical School, São Paulo, SP 05403-000, Brazil.
Tábita HünemeierHuman Population Genomics Laboratory, Department of Genetics and Evolutionary Biology, University of São Paulo, São Paulo, SP 05508-090, Brazil.
Lygia V PereiraNational Laboratory for Embryonic Stem Cell Research, Department of Genetics and Evolutionary Biology, University of São Paulo, São Paulo, SP 05508-090, Brazil.
Christina MitropoulouThe Golden Helix Foundation, London WC2N 5AP, UK.
Universidade de São Paulo · BRGolden Helix Foundation · GBUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the post-genomic era, genomic medicine interventions as a key component of personalized medicine and tailored-made health care are greatly anticipated following recent scientific and technological advances. Indeed, large-scale sequencing efforts that explore human genomic variation have been initiated in several, mostly developed, countries across the globe, such as the United States, the United Kingdom, and a few others. Here, we highlight the successful implementation of large-scale national genomic initiatives, namely the Genome of Greece (GoGreece) and the DNA do Brasil (DNABr), aiming to emphasize the importance of implementing such initiatives in developing countries. Based on this experience, we also provide a roadmap for replicating these projects in other low-resource settings, thereby bringing genomic medicine in these countries closer to clinical fruition.

Indexed as

Genome, HumanBrazilDeveloping CountriesGenetics, MedicalGenomicsGreeceHigh-Throughput Nucleotide SequencingHumansOne HealthPrecision MedicinePublic HealthUnited KingdomUnited Statesgenomic medicineimplementationlarge-scale genomics initiativeslow- and medium-income countriespersonalized medicine

Identifiers

PMID33007198
PMCPMC7536572
OpenAlexW3090155776

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.