ArticlePloS one2020
Morphological peculiarities of the DNA-protein complexes in starved Escherichia coli cells.
Article in PloS one, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 47 citations in OpenAlex.
- Bacterial extracellular vesicles as recyclable nutrient reservoirs.Nature communications · 2026Article
- Investigation of the Mechanisms of Transition of Gram-Negative Bacterial Cells into Induced Anabiosis Using Computational Methods of Classical Molecular Dynamics.Microorganisms · 2026Article
- Structural and Binding Properties of Dps - A Nucleoid Associated Protein.bioRxiv : the preprint server for biology · 2025Article
- The Dps Protein ProtectsInternational journal of molecular sciences · 2025Article
- Bridging DNA contacts allow Dps from E. coli to condense DNA.Nucleic acids research · 2024Article
- Dynamic action of an intrinsically disordered protein in DNA compaction that induces mycobacterial dormancy.Nucleic acids research · 2024Article
- Bridging DNA contacts allow Dps frombioRxiv : the preprint server for biology · 2024Article
- Determination of DNA architecture of bacteria under various types of stress, methodological approaches, problems, and solutions.Biophysical reviews · 2023Review
- Biodegradable Water-Soluble Matrix for Immobilization of Biocidal 4-Hexylresorcinol.International journal of molecular sciences · 2023Article
- DNA-Binding Protein Dps ProtectsBiology · 2023Article
- Article
- Biocidal Coatings from Complexes of Carboxylated Latex Particles and a Linear Cationic Polymer.Polymers · 2022Article
- Small Prokaryotic DNA-Binding Proteins Protect Genome Integrity throughout the Life Cycle.International journal of molecular sciences · 2022Review
- Pathological ATX3 Expression Induces Cell Perturbations inInternational journal of molecular sciences · 2021Article
- Maturation of Pseudo-Nucleus Compartment inViruses · 2020Article
- Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the adaptive strategies for the constantly changing conditions of the environment utilized in bacterial cells involves the condensation of DNA in complex with the DNA-binding protein, Dps. With the use of electron microscopy and electron tomography, we observed several morphologically different types of DNA condensation in dormant Escherichia coli cells, namely: nanocrystalline, liquid crystalline, and the folded nucleosome-like. We confirmed the presence of both Dps and DNA in all of the ordered structures using EDX analysis. The comparison of EDX spectra obtained for the three different ordered structures revealed that in nanocrystalline formation the majority of the Dps protein is tightly bound to nucleoid DNA. The dps-null cells contained only one type of condensed DNA structure, liquid crystalline, thus, differing from those with Dps. The results obtained here shed some light on the phenomenon of DNA condensation in dormant prokaryotic cells and on the general problem of developing a response to stress. We demonstrated that the population of dormant cells is structurally heterogeneous, allowing them to respond flexibly to environmental changes. It increases the ability of the whole bacterial population to survive under extreme stress conditions.
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