Evidence map›Paper›PMID 33006674›Full record

ArticleZeitschrift fur Rheumatologie2021

What can hand sonography and nerve conduction velocity disclose regarding hand dysfunction in rheumatoid arthritis patients?

E A Abda, M M Hassanien, E Abdelrazek, S A Mahran

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Article in Zeitschrift fur Rheumatologie, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

E A AbdaRheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt.
M M HassanienRheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt.
E AbdelrazekRheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt.
S A MahranRheumatology and Rehabilitation Department, Assiut University, Assiut, Egypt. safaa.mahran@aun.edu.eg.
Assiut University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundHand function in rheumatoid arthritis (RA) is a major determinant of functional ability.

objectiveTo explore hand dysfunction in RA patients and to investigate the role of ultrasonography and nerve conduction studies in detecting factors affecting hand dysfunction. PATIENTS AND

methodsOne hundred RA patients were included in this cross-sectional study and subgrouped into those with a weak hand grip (group A) and those with a good hand grip (group B). Ultrasonographic examinations and nerve conduction studies were performed. Multiple regression analysis and receiver operating characteristic curves were used.

resultsThe age of enrolled patients was 45.16 ± 11.66 years, 88% were females. Patients in group A had poorer hand function and quality of life compared to those in group B (P < 0.001). Using musculoskeletal ultrasonography (MSUS), higher scores of synovial proliferation, bone erosion, and cartilage damage were found in group A. Hands with weak grip strength had reduced sensory median and ulnar conduction velocity than those with good grip (P = 0.02 and 0.01, respectively). The grip strength test had 92% sensitivity and 95% specificity for prediction of hand dysfunction, while upon combining synovial proliferation with ulnar nerve sensory latency and the grip strength test, the greatest sensitivity (98%) was reached with 55% specificity.

conclusionMedian and ulnar sensory conduction changes together with signs of chronic inflammation and joint destruction in MSUS are prevalent in patients with poor hand grip. Combined grip strength, ulnar nerve sensory conduction study, and synovial proliferation could represent a sensitive predictor of hand dysfunction in RA.

Indexed as

Arthritis, RheumatoidHand StrengthAdultCross-Sectional StudiesFemaleHandHumansMiddle AgedNeural ConductionQuality of LifeUltrasonographyGrip strengthJoint erosionPredictorsQuality of lifeUlnar sensory latency

Identifiers

PMID33006674
OpenAlexW3090647632

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.