Evidence map›Paper›PMID 33006667›Full record

ReviewMolecular genetics and genomics : MGG2021

Recent advances on the machine learning methods in predicting ncRNA-protein interactions.

Lin Zhong, Meiqin Zhen, Jianqiang Sun, Qi Zhao

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular genetics and genomics : MGG, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Metamorphosis and lncRNAs: A Close Relationship.Genesis (New York, N.Y. : 2000) · 2026
    Review
  2. Review
  3. Review
  4. Review
  5. lncHUB2: aggregated and inferred knowledge about human and mouse lncRNAs.Database : the journal of biological databases and curation · 2023
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Lin Zhong *School of Mathematics, Liaoning University, Shenyang, 110036, China.
Meiqin Zhen *Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, 101149, China.
Jianqiang SunSchool of Automation and Electrical Engineering, Linyi University, Linyi, 276000, China.
Qi ZhaoSchool of Computer Science and Software Engineering, University of Science and Technology Liaoning, Anshan, 114051, China. zhaoqi@lnu.edu.cn.ORCID http://orcid.org/0000-0001-9713-1864
Capital Medical University · CNLiaoning University · CNLinyi University · CNUniversity of Science and Technology Liaoning · CN

Funding

National Natural Science Foundation of China 11805091
6 · The paper itself

Abstract

Recent transcriptomics and bioinformatics studies have shown that ncRNAs can affect chromosome structure and gene transcription, participate in the epigenetic regulation, and take part in diseases such as tumorigenesis. Biologists have found that most ncRNAs usually work by interacting with the corresponding RNA-binding proteins. Therefore, ncRNA-protein interaction is a very popular study in both the biological and medical fields. However, due to the limitations of manual experiments in the laboratory, machine-learning methods for predicting ncRNA-protein interactions are increasingly favored by the researchers. In this review, we summarize several machine learning predictive models of ncRNA-protein interactions over the past few years, and briefly describe the characteristics of these machine learning models. In order to optimize the performance of machine learning models to better predict ncRNA-protein interactions, we give some promising future computational directions at the end.

Indexed as

Machine LearningComputational BiologyGene Regulatory NetworksHumansRNA-Binding ProteinsRNA, Long NoncodingRNA-Binding ProteinsRNA, Long NoncodingMachine learning methodsncRNAncRNA-protein interactionPredictive modelsProtein

Identifiers

PMID33006667
OpenAlexW3090646294

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.