Evidence map›Paper›PMID 33006665›Full record

ArticleClinical oral investigations2021

Biocompatibility, mechanical, and bonding properties of a dental adhesive modified with antibacterial monomer and cross-linker.

Hoda Moussa, Megan M Jones, Ningbo Huo, Runsheng Zhang, Mayuresh Keskar, Michelle B Visser, Mark T Swihart, Chong Cheng, Camila Sabatini

Abstract read
PubMed Publisher
In one paragraph

Article in Clinical oral investigations, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Hoda MoussaDepartment of Chemistry, Buffalo State College, 1300 Elmwood Avenue, Buffalo, NY, 14222, USA.
Megan M JonesDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, 3435 Main Street, Buffalo, NY, 14214, USA.
Ningbo HuoDepartment of Chemical and Biological Engineering, School of Engineering, University at Buffalo, Furnas Hall, #310, Buffalo, NY, 14260, USA.
Runsheng ZhangDepartment of Chemical and Biological Engineering, School of Engineering, University at Buffalo, Furnas Hall, #310, Buffalo, NY, 14260, USA.
Mayuresh KeskarDepartment of Chemical and Biological Engineering, School of Engineering, University at Buffalo, Furnas Hall, #310, Buffalo, NY, 14260, USA.
Michelle B VisserDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, 3435 Main Street, Buffalo, NY, 14214, USA.
Mark T SwihartDepartment of Chemical and Biological Engineering, School of Engineering, University at Buffalo, Furnas Hall, #310, Buffalo, NY, 14260, USA.
Chong ChengDepartment of Chemical and Biological Engineering, School of Engineering, University at Buffalo, Furnas Hall, #310, Buffalo, NY, 14260, USA.
Camila SabatiniDepartment of Restorative Dentistry, School of Dental Medicine, University at Buffalo, 215 Squire Hall, 3435 Main Street, Buffalo, NY, 14214, USA. cs252@buffalo.edu.ORCID http://orcid.org/0000-0003-0388-5206
University at Buffalo, State University of New York · USBuffalo State University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study investigated the antibacterial, cytotoxicity, and mechanical properties of a dental adhesive modified with quaternary ammonium monomer ((2-acryloyloxyethyl)dimethyldodecylammonium bromide) and cross-linker (bis(2-acryloyloxyethyl)methyldodecylammonium bromide). MATERIALS AND

methodsMonomer (M), cross-linker (C), or a combination of these (M + C) were incorporated into adhesive Adper Single Bond Plus (SB) in 5, 10, or 25% (as wt%). A colony-forming unit and MTT assays were used to evaluate antibacterial properties against Streptococcus mutans and cell viability. Resin-dentin beams (0.9 ± 0.1 mm

results10%M and 25%M demonstrated a significant reduction in S. mutans relative to SB (p < 0.001). No differences in cytotoxicity were detected for any of the groups. After 6 months, no changes in μTBS were shown for any of the groups. After 3 years, all groups evidenced a significant decrease in μTBS (p < 0.05) except 5%M, 5%C, and 5%M + 5%C. All groups demonstrated either stable or significantly increased UTS after 6 months. Except for the cross-linker groups, a significant decrease in micro-hardness was shown for all groups after softening in ethanol (p < 0.05).

conclusionsA 5-10% of monomer may render the resin antibacterial without a compromise to its mechanical and bonding properties. CLINICAL RELEVANCE: Biomodification of a resin adhesive with an antibacterial monomer and cross-linker may help improve the life span of adhesive restorations.

Indexed as

Dental BondingResin CementsAnti-Bacterial AgentsComposite ResinsDental CementsDentinDentin-Bonding AgentsHumansMaterials TestingTensile StrengthAnti-Bacterial AgentsComposite ResinsDental CementsDentin-Bonding AgentsResin CementsAdhesionAntibacterialBond strengthCross-linkerMonomer

Identifiers

PMID33006665
OpenAlexW3091108972

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.