Evidence map›Paper›PMID 33006331›Full record

ArticleRhinology2021

The Olfactory Cleft Endoscopy Scale: a multi-institutional validation study in chronic rhinosinusitis.

R J Schlosser, T L Smith, J C Mace, J A Alt, D M Beswick, J L Mattos, V Ramakrishnan, C Massey, Z M Soler

Abstract readMulticenter StudyValidation Study
In one paragraph

Article in Rhinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Review
  3. Distinct inflammatory patterns and nasal bacterial dysbiosis in uncontrolled chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2025
    Article
  4. Subjective versus Psychophysical Measures of Chemosensory Alterations following COVID-19.ORL; journal for oto-rhino-laryngology and its related specialties · 2024
    Article
  5. Article
  6. [A prospective study of the effect of functional endoscopic sinus surgery on the recovery of olfactory function in patients with chronic rhinosinusitis with nasal polyposis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2023
    Article
  7. Association between cognition and olfaction-specific parameters in patients with chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2023
    Article
  8. Predictive significance of the questionnaire of olfactory disorders-negative statements for olfactory loss in patients with chronic rhinosinusitis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
  9. [Application research and development of objective examination of olfactory function].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R J SchlosserDivision of Rhinology and Sinus Surgery, Medical University of South Carolina, Charleston, SC, USA.
T L SmithDivision of Rhinology and Sinus Surgery, Oregon Health Services University, Portland, OR, USA.
J C MaceDivision of Rhinology and Sinus Surgery, Oregon Health Services University, Portland, OR, USA.
J A AltUniversity of Utah, Salt Lake City, UT, USA.
D M BeswickUniversity of Colorado, Aurora, CO, USA.
J L MattosUniversity of Virginia, Charlottesville, VA, USA.
V RamakrishnanUniversity of Colorado, Aurora, CO, USA.
C MasseyUniversity of Colorado, Aurora, CO, USA.
Z M SolerDivision of Rhinology and Sinus Surgery, Medical University of South Carolina, Charleston, SC, USA.

Funding

DETERMINANTS OF SURGICAL OUTCOMES IN CHRONIC SINUSITISR01DC005805 · NIDCD · OREGON HEALTH & SCIENCE UNIVERSITY · PI SMITH, TIMOTHY L, SOLER, ZACHARY M · 2004 to 2020
$7.6M
NIDCD NIH HHS R01 DC005805
6 · The paper itself

Abstract

backgroundOlfactory dysfunction (OD) associated with chronic rhinosinusitis (CRS) remains quite challenging. Instruments to precisely assess olfactory cleft anatomy and their association with olfaction are needed.

methodsThe olfactory cleft endoscopy scale (OCES) was used to assess the olfactory cleft in healthy control subjects and a cohort of patients with CRS. Psychophysical and psychosocial olfactory function were assessed and correlations with OCES scores were measured.

resultsControl subjects and subjects with CRS with nasal polyps (CRSwNP) and CRS without nasal polyps (CRSsNP) were enrol- led. OCES correlated with both psychophysical and psychosocial olfaction, as measured by threshold, discrimination and identi- fication (TDI) scores and Questionnaire on Olfactory Disorders (QOD-NS) scores for all case and control subjects combined. OCES improved in both CRS groups postoperatively with the highest correlation seen in postoperative olfaction in CRSwNP patients. CRS patients who achieve near perfect OCES and sinus endoscopy scores after surgery have olfactory metrics that are indistin- guishable from controls regardless of polyp status.

conclusionsThe OCES is a valid olfactory-specific measure that demonstrates strong validity and provides complimentary infor- mation to traditional sinus endoscopy to aid in our understanding of OD associated with CRS.

Indexed as

Nasal PolypsOlfaction DisordersRhinitisSinusitisChronic DiseaseEndoscopyHumansSmell

Identifiers

PMID33006331
PMCPMC8117779

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.