ArticleDysphagia2021
The Influence of Airflow Via High-Flow Nasal Cannula on Duration of Laryngeal Vestibule Closure.
Article in Dysphagia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- The effects of flow settings during high-flow nasal cannula support for adult subjects: a systematic review.Critical care (London, England) · 2023Pooled it
- The effects of noninvasive respiratory support on swallowing physiology, airway protection, and respiratory-swallow pattern in adults: A systematic review.Respiratory medicinePooled it
- Oral Feeding and Aspiration Risk in Preterm Infants Receiving Nasal High-Flow Respiratory Support: A Cross-Sectional Study.Dysphagia · 2026Article
- Role of High flow nasal cannula in managing Type I respiratory failure in patients with neuromuscular disorders.BMC pulmonary medicine · 2026Article
- Current Technological Advances in Dysphagia Screening: Systematic Scoping Review.Journal of medical Internet research · 2025Article
- Article
- Swallowing during provision of helmet ventilation: Review and provisional multidisciplinary guidance.Journal of the Intensive Care Society · 2024Article
- Effects of high-flow nasal therapy on swallowing function: a scoping review.ERJ open research · 2024Article
- A Survey of Feeding Practices During High-Flow Nasal Cannula Oxygen Therapy.Respiratory care · 2023Article
- The upper airway parameters: the potential diagnostic clues for congenital intrathoracic lesions.BMC pregnancy and childbirth · 2023Observational
- Treatment of Pediatric Patients With High-Flow Nasal Cannula and Considerations for Oral Feeding: A Review of the Literature.Perspectives of the ASHA special interest groups · 2022Article
- Nutrition Therapy in Non-intubated Patients with Acute Respiratory Failure.Current nutrition reports · 2021Review
- Exploring Practice Approaches and Opinions of International Speech and Language Therapists in the Assessment and Management of Oropharyngeal Swallowing in Adults on High-flow Nasal Oxygen: A Focus Group Study.International journal of language & communication disordersArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this experimental study was to investigate the influence of airflow via high-flow nasal cannula (HFNC) on the duration of laryngeal vestibule closure (dLVC) and Penetration-Aspiration Scale (PAS) scores. Twenty-nine healthy adults participated in a repeated-measures design. Each participant completed a videofluoroscopic swallow study while receiving airflow via HFNC across a control condition of zero flow and conditions of 10, 20, 30, 40, 50, and 60 L/min. Five raters rated dLVC and PAS scores. Laryngeal vestibule closure was complete on all swallows. Linear regression revealed that the amount of airflow via HFNC significantly influenced dLVC, F(1, 810) = 19.056, p < .001. The mode of airway invasion for each airflow condition was PAS 2, with > 80% frequency compared to other PAS scores. Aspiration (PAS 7 or 8) did not occur. A Fisher's Exact test determined there was no association between normal/abnormal PAS score and no airflow/HFNC (p = .610). Findings indicate that for healthy adults, airflow via HFNC influenced dLVC in a dose-dependent manner with no change in airway invasion. The influence of HFNC on dLVC was a positive relationship, meaning when airflow increased, dLVC increased, and when airflow decreased, dLVC decreased. Modulation of dLVC in response to the amount of airflow highlights the ability of healthy adults to adapt to swallow conditions as needed to protect the airway.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.