Evidence map›Paper›PMID 33005891›Full record

ArticleBrain communications2020

Hypokalaemic periodic paralysis with a charge-retaining substitution in the voltage sensor.

Tomoya Kubota, Fenfen Wu, Savine Vicart, Maki Nakaza, Damien Sternberg, Daisuke Watanabe, Mitsuru Furuta, Yosuke Kokunai, Tatsuya Abe, Norito Kokubun and 3 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Periodic paralysis.Handbook of clinical neurology · 2024
    Review
  3. Article
  4. Review
  5. Fifty years of gating currents and channel gating.The Journal of general physiology · 2023
    Review
  6. CaHandbook of experimental pharmacology · 2023
    Article
  7. Voltage-dependent CaAmerican journal of physiology. Cell physiology · 2022
    Article
  8. Article
  9. Voltage-Gated CaFrontiers in synaptic neuroscience · 2021
    Review
  10. Case Report: A NovelFrontiers in genetics · 2021
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Tomoya KubotaDivision of Health Sciences, Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, 1-7, Yamadaoka, Suita, Osaka, 5650871, Japan.
Fenfen WuDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Savine VicartSorbonne Université, INSERM, Assistance Publique -Hôpitaux de Paris, Center of Research in Myology-UMR 974, Service of Neuro-Myology (CMR Muscle Channelopathies), Institute of Myology, University Hospital Pitié-Salpêtrière, Paris, France.
Maki NakazaDivision of Health Sciences, Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, 1-7, Yamadaoka, Suita, Osaka, 5650871, Japan.
Damien SternbergSorbonne Université, INSERM, Assistance Publique -Hôpitaux de Paris, Center of Research in Myology-UMR 974, Service of Neuro-Myology (CMR Muscle Channelopathies), Institute of Myology, University Hospital Pitié-Salpêtrière, Paris, France.
Daisuke WatanabeDepartment of Neurology, National Hospital Organization Hakone Hospital, Odawara, Japan.
Mitsuru FurutaDepartment of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Yosuke KokunaiDepartment of Neurology, Osaka University Graduate School of Medicine, Suita, Osaka, Japan.
Tatsuya AbeDepartment of Neurology, National Hospital Organization Hakone Hospital, Odawara, Japan.
Norito KokubunDepartment of Neurology, Dokkyo Medical University, Tochigi, Japan.
Bertrand FontaineSorbonne Université, INSERM, Assistance Publique -Hôpitaux de Paris, Center of Research in Myology-UMR 974, Service of Neuro-Myology (CMR Muscle Channelopathies), Institute of Myology, University Hospital Pitié-Salpêtrière, Paris, France.
Stephen C CannonDepartment of Physiology, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Masanori P TakahashiDivision of Health Sciences, Department of Functional Diagnostic Science, Osaka University Graduate School of Medicine, 1-7, Yamadaoka, Suita, Osaka, 5650871, Japan.ORCID 0000-0002-5513-5012

Funding

Disease Pathogenesis and Modification for CaV1.1-Associated Hypokalemic Periodic ParalysisR01AR063182 · NIAMS · UT SOUTHWESTERN MEDICAL CENTER · PI STEPHEN C. CANNON · 2012 to 2026
$6.0M
NIAMS NIH HHS R01 AR063182
6 · The paper itself

Abstract

Familial hypokalaemic periodic paralysis is a rare skeletal muscle disease caused by the dysregulation of sarcolemmal excitability. Hypokalaemic periodic paralysis is characterized by repeated episodes of paralytic attacks with hypokalaemia, and several variants in

Indexed as

CaVgating pore currenthypokalaemic periodic paralysisNaVvoltage sensing domain

Identifiers

PMID33005891
PMCPMC7519726

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.