Evidence map›Paper›PMID 33005835›Full record

ArticleTranslational medicine of aging2020

Extracellular vesicles and extracellular RNA in aging and age-related disease.

Nicole Noren Hooten

Open access · goldAbstract read
In one paragraph

Article in Translational medicine of aging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Proteome of CD9Life (Basel, Switzerland) · 2026
    Article
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  7. Article
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  11. Research progress of extracellular vesicles in type 2 diabetes and its complications.Diabetic medicine : a journal of the British Diabetic Association · 2022
    Review
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  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Nicole Noren HootenLaboratory of Epidemiology and Population Science, National Institute on Aging, National Institutes of Health, 251 Bayview Boulevard, Baltimore, MD, 21224, USA.
National Institutes of Health · US

Funding

Healthy Aging Neighborhoods of Diversity Across LifespanZ01AG000513 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2001 to 2008
$6.8M
Characterization of Serum Extracellular Vesicles with Human AgeZIAAG000989 · NIA · NATIONAL INSTITUTE ON AGING · PI EVANS, MICHELE K · 2017 to 2025
$4.1M
PERIPHERAL NEUROPATHY, SENSORIMOTOR FUNCTIONS &BALANCEK23AG000989 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RICHARDSON, JAMES K · 2000 to 2004
$711k
Intramural NIH HHS Z01 AG000513Intramural NIH HHS ZIA AG000989NIA NIH HHS K23 AG000989
6 · The paper itself

Abstract

Circulating factors are well known to influence aging and age-related disease. As part of the Aging Science Talks: Science for the Community series, data was presented on two types of circulating functional biomarkers: extracellular RNA (exRNA) and extracellular vesicles (EVs). EVs in the context of type 2 diabetes mellitus was also discussed, as this is an area of interest due to the growing global epidemic of this age-related disease.

Indexed as

BiomarkerEVExosomeexRNAMicroparticlemicroRNAMicrovesicleType 2 diabetes mellitus

Identifiers

PMID33005835
PMCPMC7526621
OpenAlexW3045261872

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.