ArticleAmerican journal of ophthalmology case reports2020
Paraneoplastic acute exudative polymorphous vitelliform maculopathy improved with intravitreal methotrexate.
Article in American journal of ophthalmology case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Paraneoplastic vitelliform retinopathy successfully treated with intravitreal dexamethasone implants.American journal of ophthalmology case reports · 2026Article
- Paraneoplastic syndromes and the retina.Current opinion in ophthalmology · 2026Review
- [Metallic shiny visual phenomena in a female patient with pancreatic cancer].Die Ophthalmologie · 2023Article
- A comprehensive review of intravitreal immunosuppressants and biologicals used in ophthalmology.Therapeutic advances in ophthalmologyReview
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Authors and funding
4 authors.
Funding
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Abstract
purposeTo describe a case of acute exudative polymorphous vitelliform maculopathy (AEPVM) treated with intravitreal methotrexate. OBSERVATIONS: A 58-year-old man with a history of metastatic melanoma developed paraneoplastic acute exudative polymorphous vitelliform maculopathy, refractory to oral prednisone, intravitreal bevacizumab and intravitreal preservative-free triamcinolone. Improvement in vision and resolution of subfoveal fluid was later seen after intravitreal methotrexate therapy. CONCLUSIONS AND IMPORTANCE: AEPVM is a rare and poorly understood retinal disorder that may be idiopathic or may manifest in patients with malignancies. The pathogenic process is thought to be an attack directed against the retinal pigment epithelium (RPE) and photoreceptors. Intravitreal methotrexate may provide benefit when treating AEPVM, especially when trials of steroids and anti-VEGF medications have failed.
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