Evidence map›Paper›PMID 33005774›Full record

ArticleHeliyon2020

Iodine-131 labeled genistein as a potential radiotracer for breast cancer.

Danni Ramdhani, Eva Maria Widyasari, Maula Eka Sriyani, Quinzheilla Putri Arnanda, Hiroshi Watabe

Open access · goldAbstract read
In one paragraph

Article in Heliyon, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Danni RamdhaniDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java 45363, Indonesia.
Eva Maria WidyasariApplied Nuclear Science and Technology Center (PSTNT), National Nuclear Energy Agency of Indonesia (BATAN), Bandung, West Java 40116, Indonesia.
Maula Eka SriyaniApplied Nuclear Science and Technology Center (PSTNT), National Nuclear Energy Agency of Indonesia (BATAN), Bandung, West Java 40116, Indonesia.
Quinzheilla Putri ArnandaDepartment of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Padjadjaran University, Sumedang, West Java 45363, Indonesia.
Hiroshi WatabeDivision of Radiation Protection and Safety Control, Cyclotron and Radioisotope Center, Tohoku University, Sendai, Japan.
National Nuclear Energy Agency of Indonesia · IDTohoku University · JPPadjadjaran University · ID

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveGenistein is an isoflavone compound that has been proven to have anticancer activity and is capable of binding to estrogen β receptors with Selective Estrogen Receptor Modulators (SERMs) properties, and has a strong affinity to inhibit the development of cancer cells. This study is to determine the optimum conditions of the reaction in the synthesis process of compounds labeled

methodsSynthesis of

resultsOptimization of the synthesis conditions of the

conclusionProducts labeled

Indexed as

Breast cancerEstrogen receptors betaGenesteinIodine-131Pharmaceutical chemistryRadiotracer

Identifiers

PMID33005774
PMCPMC7509807
OpenAlexW3089162291

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.