Evidence map›Paper›PMID 33005564›Full record

ArticleJournal of oral biology and craniofacial research

Evaluation of serum immunoglobulin (IgG, IgM, IgA) in potentially malignant disorders of oral cavity - A case control study.

Vivek M Tarsariya, Dhaval N Mehta, Nilesh Raval, Hiren H Patadiya, Kanan Vachhrajani, Albert Ashem

Open access · greenAbstract read
In one paragraph

Article in Journal of oral biology and craniofacial research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Vivek M TarsariyaShantabaa Medical College & General Hospital, Amreli, Gujarat, India.
Dhaval N MehtaDept. of Oral Medicine & Radiology, Narsinhbhai Patel Dental College & Hospital, Visnagar, Gujarat, India.
Nilesh RavalDept. of Oral Medicine & Radiology, Karnavati School of Dentistry, Uvarsad, Gandhinagar, Gujarat, India.
Hiren H PatadiyaBoston University, Henry M Goldman School of Dental Medicine, Boston, USA.
Kanan VachhrajaniUniversity of Toronto, Canada.
Albert AshemDental College, RIMS, Imphal, Manipur, India.
Boston University · USManubhai Patel Dental College and Hospital · INRegional Institute of Medical Sciences · INUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOnly few studies have been done to evaluate level of serum immunoglobulins (IgG,IgM,IgA) in patients with Potentially Malignant Disorders (PMD) like Leukoplakia, Oral Submucous Fibrosis (OSMF) and Oral Lichen Planus (OLP) as tumour markers. AIMS AND

objectivesTo estimate the serum immunoglobulins level (IgG, IgM, IgA) in leukoplakia, OSMF and oral lichen planus (OLP) patients and its comparison with levels among control groups and Weather these values can be used to predict severity of disease or not. MATERIALS AND

methods30 patients with different potentially malignant disorders like leukoplakia, OSMF and oral lichen planus and 30 healthy controls were selected at random and subjected for analysis of serum IgG, IgA, IgM. Statistical methods employed were mean, standard deviation and ANOVA test.

resultsWe observed significant elevated levels of all the immunoglobulins in leukoplakia, OSMF and oral lichen planus when compared with the control group and levels were increasing with clinical stages of OSMF

conclusionsAll these immunoglobulins are indicative of tumour burden or transformation of malignancy in higher stage and might be employed as prognostic indicators in these disorders.

Indexed as

IgAIgGIgMPotentially malignant disorderSerum immunoglobulinTumour marker

Identifiers

PMID33005564
PMCPMC7511741
OpenAlexW3084111067

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.