Evidence map›Paper›PMID 33005474›Full record

ArticleLiver research (Beijing, China)2020

Lijun Wang, Yu-Shiuan Wang, Eko Mugiyanto, Wei-Chiao Chang, Yu-Jui Yvonne Wan

Open access · goldAbstract read
In one paragraph

Article in Liver research (Beijing, China), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The Role of microRNA-22 in Metabolism.International journal of molecular sciences · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. miR-22 gene therapy treats HCC by promoting anti-tumor immunity and enhancing metabolism.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 3 countries.

Lijun WangDepartment of Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA.
Yu-Shiuan WangPhD Program in Clinical Drug Development of Chinese Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei.
Eko MugiyantoPhD Program in Clinical Drug Development of Chinese Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei.
Wei-Chiao ChangPhD Program in Clinical Drug Development of Chinese Herbal Medicine, College of Pharmacy, Taipei Medical University, Taipei.
Yu-Jui Yvonne WanDepartment of Pathology and Laboratory Medicine, University of California Davis, Sacramento, CA.
Taipei Medical University · TWUniversity of California, Davis · US

Funding

The Role of Probiotic Bifidobacteria and Bile Acid Metabolism in CarcinogenesisU01CA179582 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI MILLS, DAVID ANDREW, SLUPSKY, CAROLYN · 2014 to 2018
$2.8M
Liver Cancer Therapy by MiR-22 and Its InducersR01CA222490 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI WAN, YU-JUI YVONNE · 2018 to 2023
$2.1M
NCI NIH HHS R01 CA222490NCI NIH HHS U01 CA179582
6 · The paper itself

Abstract

With obesity rate consistently increasing, a strong relationship between obesity and fatty liver disease has been discovered. More than 90% of bariatric surgery patients also have non-alcoholic fatty liver diseases (NAFLDs). NAFLD and non-alcoholic steatohepatitis (NASH), which are the hepatic manifestations of metabolic syndrome, can lead to liver carcinogenesis. Unfortunately, there is no effective medicine that can be used to treat NASH or liver cancer. Thus, it is critically important to understand the mechanism underlying the development of these diseases. Extensive evidence suggests that microRNA 22 (

Indexed as

CancerHepatitisLiverMetabolismMicroRNA-22(miR-22)Non-alcoholic steatohepatitisSteatosis

Identifiers

PMID33005474
PMCPMC7523703
OpenAlexW3034726395

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.