Evidence map›Paper›PMID 33005459›Full record

ArticleCase reports in dentistry2020

Gingival Biopsy to Detect Mosaicism in Overgrowth Syndromes: Report of Two Cases of Megalencephaly-Capillary Malformation Syndrome with Periodontal Anomalies.

Mathieu Marty, Carole Bonnaud, Natalie Jones, Michel Longy, Frédéric Vaysse, Eric Bieth, Isabelle Bailleul-Forestier

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Case reports in dentistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mathieu MartyPaul Sabatier Toulouse III University, Department of Paediatric Dentistry, CHU Toulouse, F-31000, France.ORCID https://orcid.org/0000-0003-0579-341X
Carole BonnaudPaul Sabatier Toulouse III University, Department of Paediatric Dentistry, CHU Toulouse, F-31000, France.
Natalie JonesCancer Genetics Unit & INSERM U1218, Institut Bergonié, Bordeaux University, Bordeaux, France.
Michel LongyCancer Genetics Unit & INSERM U1218, Institut Bergonié, Bordeaux University, Bordeaux, France.
Frédéric VayssePaul Sabatier Toulouse III University, Department of Paediatric Dentistry, CHU Toulouse, F-31000, France.
Eric BiethPaul Sabatier Toulouse III University, Genetics Unit, CHU Toulouse, F-3100, France.
Isabelle Bailleul-ForestierPaul Sabatier Toulouse III University, Department of Paediatric Dentistry, CHU Toulouse, F-31000, France.
Université Toulouse III - Paul Sabatier · FRInserm · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMegalencephaly-capillary malformation (MCAP) is a rare overgrowth syndrome caused by postzygotic activating mutations in the

aimTo illustrate the benefits of gingival biopsy in the genetic diagnosis of overgrowth syndromes.

designGingival biopsy was performed on a 13-year-old patient and a 16-year-old patient with MCAP and who suffered from periodontal disease.

resultsPathogenic p.Glu365Lys and p.Glu545Asp

conclusionsConsidering the tissue distribution and level of somatic mosaicism for

Identifiers

PMID33005459
PMCPMC7509567
OpenAlexW3085904028

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.