Evidence map›Paper›PMID 33005177›Full record

ArticleFrontiers in genetics2020

The Association Between Breast Cancer and Blood-Based Methylation of

Qiming Yin, Xiaoqin Yang, Lixi Li, Tian Xu, Wenjie Zhou, Wanjian Gu, Fei Ma, Rongxi Yang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. The association between blood-basedLung cancer management · 2025
    Article
  2. Frontiers in endocrinology · 2025
    Article
  3. Article
  4. Epigenetics · 2024
    Article
  5. Article
  6. Article
  7. The association betweenFrontiers in oncology · 2023
    Article
  8. Article
  9. Article
  10. The association betweenFrontiers in cardiovascular medicine · 2022
    Article
  11. Article
  12. [Peripheral bloodNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2021
    Article
  13. Frontiers in neuroscience · 2021
    Article
  14. [Association betweenNan fang yi ke da xue xue bao = Journal of Southern Medical University
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Qiming YinDepartment of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Xiaoqin YangDepartment of Breast Surgery, West China Hospital, Sichuan University, Chengdu, China.
Lixi LiDepartment of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Tian XuDepartment of Clinical Laboratory, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Wenjie ZhouChengdu Shang Jin Nan Fu Hospital, West China Hospital, Sichuan University, Chengdu, China.
Wanjian GuDepartment of Clinical Laboratory, Jiangsu Province Hospital of Chinese Medicine, Nanjing, China.
Fei MaDepartment of Medical Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Rongxi YangDepartment of Epidemiology and Biostatistics, School of Public Health, Nanjing Medical University, Nanjing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNJiangsu Province Hospital · CNNanjing Medical University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous work has shown that DNA methylation in peripheral blood may be associated with malignancy; however, these studies have mainly been conducted within Caucasian populations. Here, we investigated the association between blood-based methylation of S100 calcium-binding protein P gene (

Indexed as

breast cancerDNA methylationepigenomicshyaluronoglucosaminidase 2 geneS100 calcium-binding protein P gene

Identifiers

PMID33005177
PMCPMC7485126
OpenAlexW3081741439

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.