Evidence map›Paper›PMID 33005114›Full record

ArticleThe Yale journal of biology and medicine2020

Paraneoplastic Limbic Encephalitis in a Patient with Primary Well-differentiated Teratoma and Metastatic Poorly Differentiated Embryonal Carcinoma.

Chase J Wehrle, Asad Ullah, Margaret A Sinkler, Saleh G Heneidi, Zachary Klaassen, Paul Biddinger, Edward J Kruse, Gerald Wallace, Fenwick Nichols, Nikhil Patel

Open access · greenAbstract readCase Reports
PubMed Full text at PMC
In one paragraph

Article in The Yale journal of biology and medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 85% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Chase J WehrleMedical College of Georgia, Augusta, GA.
Asad UllahDepartment of Pathology, Medical College of Georgia, Augusta, GA.
Margaret A SinklerMedical College of Georgia, Augusta, GA.
Saleh G HeneidiDepartment of Pathology, Medical College of Georgia, Augusta, GA.
Zachary KlaassenDepartment of Urology, Medical College of Georgia, Augusta, GA.
Paul BiddingerDepartment of Pathology, Medical College of Georgia, Augusta, GA.
Edward J KruseDepartment of Surgical Oncology, Medical College of Georgia, Augusta, GA.
Gerald WallaceDepartment of Neurology, Medical College of Georgia, Augusta, GA.
Fenwick NicholsDepartment of Neurology, Medical College of Georgia, Augusta, GA.
Nikhil PatelDepartment of Pathology, Medical College of Georgia, Augusta, GA.
Augusta University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testicular tumors account for 1-2% of all tumors in men, with 95% of these being germ cell tumors. Paraneoplastic limbic encephalitis is a rare sequela of testicular tumors associated with anti-Ma2 and KLH11 antibodies. The most effective treatment for paraneoplastic limbic encephalitis is treatment of the primary malignancy. We report a 41-year-old male that presented to the emergency department with episodic alteration of consciousness and memory disturbances. Negative neurologic evaluation and imaging led to concern for a paraneoplastic process from a distant malignancy. CT imaging revealed an enlarged, necrotic para-aortic lymph node and subsequent ultrasound demonstrated a right-sided testicular mass. Right radical orchiectomy was performed. Microscopically, the mass consisted of mixed respiratory epithelium, gastrointestinal glands, and squamous epithelium with keratinization consistent with a post-pubertal testicular teratoma with associated

Indexed as

Carcinoma, EmbryonalLimbic EncephalitisNeoplasms, Germ Cell and EmbryonalTeratomaTesticular NeoplasmsAdultHumansMaleEmbryonal CarcinomaGerm Cell Carcinoma in situParaneoplastic Limbic EncephalitisTesticular Teratoma

Identifiers

PMID33005114
PMCPMC7513443
OpenAlexW3089578450

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.