Evidence map›Paper›PMID 33004989›Full record

ArticleScientific reports2020

The leptin to adiponectin ratio (LAR) is reduced by sleeve gastrectomy in adults with severe obesity: a prospective cohort study.

M F Rafey, C E H Fang, I Ioana, H Griffin, M Hynes, T O'Brien, O McAnena, P O'Shea, C Collins, C Davenport and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

M F RafeyBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
C E H FangBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
I IoanaBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
H GriffinBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
M HynesBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
T O'BrienBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
O McAnenaDepartment of Upper Gastrointestinal Surgery, National University of Ireland Galway, Galway, Ireland.
P O'SheaBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
C CollinsDepartment of Upper Gastrointestinal Surgery, National University of Ireland Galway, Galway, Ireland.
C DavenportBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland.
F M FinucaneBariatric Medicine Service, Centre of Diabetes, Endocrinology and Metabolism, Galway University Hospitals and HRB Clinical Research Facility, National University of Ireland, Galway, Ireland. francis.finucane@hse.ie.
Ollscoil na Gaillimhe – University of Galway · IE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bariatric surgery is known to reduce leptin and increase adiponectin levels, but the influence of sleeve gastrectomy on the leptin: adiponectin ratio (LAR), a measure of insulin sensitivity and cardiovascular risk, has not previously been described. We sought to determine the influence of sleeve gastrectomy on LAR in adults with severe obesity.In a single centre prospective cohort study of adults undergoing laparoscopic sleeve gastrectomy over a four-month period in our unit, we measured LAR preoperatively and 12 months after surgery. Of 22 patients undergoing sleeve gastrectomy, 17 (12 females, 12 with type 2 diabetes) had follow-up LAR measured at 12.1 ± 1 months. Mean body weight decreased from 130.6 ± 30.8 kg to 97.6 ± 21.6 kg, body mass index (BMI) from 46.9 ± 7.8 to 35.3 ± 7.2 kg m

Indexed as

GastrectomyAdiponectinAdultAgedFemaleHumansLeptinMaleMiddle AgedObesity, MorbidProspective StudiesAdiponectinADIPOQ protein, humanLEP protein, humanLeptin

Identifiers

PMID33004989
PMCPMC7530712
OpenAlexW3089744752

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.