ArticleScientific reports2020
Trajectories of longitudinal biomarkers for mortality in severely burned patients.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Prognostic Value of Mortality Scoring Systems in Patients With Severe Burns: Identifying Key Predictors of Mortality and Comparative Analysis Between Survivors and Non-Survivors.Medical science monitor : international medical journal of experimental and clinical research · 2026Article
- Blood biomarker trajectories in ICU-directed prediction models - A scoping review.The EPMA journal · 2026Review
- Prognostic Value of Inflammatory and Metabolic Biomarkers in ICU-Admitted Trauma Patients: A Retrospective Cohort Study.Medicina (Kaunas, Lithuania) · 2025Article
- Evaluating clinical heterogeneity and predicting mortality in severely burned patients through unsupervised clustering and latent class analysis.Scientific reports · 2023Article
- Longitudinal profile of routine biomarkers for mortality prediction using unsupervised clustering algorithm in severely burned patients: a retrospective cohort study with prospectively collected data.Annals of surgical treatment and research · 2023Article
- Evaluation of Platelet Distribution Width as an Early Predictor of Acute Kidney Injury in Extensive Burn Patients.Emergency medicine international · 2023Article
- Prediction of Mortality after Burn Surgery in Critically Ill Burn Patients Using Machine Learning Models.Journal of personalized medicine · 2022Article
- Dynamic trajectory of platelet counts after the first cycle of induction chemotherapy in AML patients.BMC cancer · 2022Article
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to investigate the differences in the trajectory of blood biomarkers routinely assessed through forward- and backward-looking approaches among burn patients. This cohort study included patients above 18 years of age from February 2007 to December 2018. All the biomarkers were estimated from admission to discharge from the intensive care unit. Significant differences were observed in the platelet count at 40 days, prothrombin time (PT) at 32 days, white blood cell count at 26 days, creatinine levels at 22 days, and lactate and total bilirubin levels at 19 days before death. In reverse order, significant differences were observed in the fitted model in platelet count at 44 days and in the platelet count and PT at 33 days. We obtained more valuable information from the longitudinal biomarker trajectory using the backward-looking method than using the forward-looking method. The platelet count served as the earliest predictor of mortality among burn patients.
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