Evidence map›Paper›PMID 33004907›Full record

ArticleScientific reports2020

Automatic classification of healthy and disease conditions from images or digital standard 12-lead electrocardiograms.

Vadim Gliner, Noam Keidar, Vladimir Makarov, Arutyun I Avetisyan, Assaf Schuster, Yael Yaniv

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Deep learning for electrocardiogram interpretation: Bench to bedside.European journal of clinical investigation · 2025
    Review
  3. Article
  4. Article
  5. Prediction of Short-Term Mortality of Cardiac Care Unit Patients Using Image-Transformed ECG Waveforms.IEEE journal of translational engineering in health and medicine · 2023
    Article
  6. Article
  7. Article
  8. Article
  9. Meeting the unmet needs of clinicians from AI systems showcased for cardiology with deep-learning-based ECG analysis.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Vadim GlinerComputer Science Department, Technion-IIT, Haifa, Israel.
Noam KeidarLaboratory of Bioenergetic and Bioelectric Systems, Biomedical Engineering Faculty, Technion-IIT, Haifa, Israel.
Vladimir MakarovSystem Programming Lab, Novgorod State University, Veliky Novgorod, Russia.
Arutyun I AvetisyanIvannikov Institute for System Programming of the Russian Academy of Sciences, Moscow, Russia.
Assaf SchusterComputer Science Department, Technion-IIT, Haifa, Israel.
Yael YanivLaboratory of Bioenergetic and Bioelectric Systems, Biomedical Engineering Faculty, Technion-IIT, Haifa, Israel. yaely@bm.technion.ac.il.
Technion – Israel Institute of Technology · ILInstitute for System Programming · RUYaroslav-the-Wise Novgorod State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Standard 12-lead electrocardiography (ECG) is used as the primary clinical tool to diagnose changes in heart function. The value of automated 12-lead ECG diagnostic approaches lies in their ability to screen the general population and to provide a second opinion for doctors. Yet, the clinical utility of automated ECG interpretations remains limited. We introduce a two-way approach to an automated cardiac disease identification system using standard digital or image 12-lead ECG recordings. Two different network architectures, one trained using digital signals (CNN-dig) and one trained using images (CNN-ima), were generated. An open-source dataset of 41,830 classified standard ECG recordings from patients and volunteers was generated. CNN-ima was trained to identify atrial fibrillation (AF) using 12-lead ECG digital signals and images that were also transformed to mimic mobile device camera-acquired ECG plot snapshots. CNN-dig accurately (92.9-100%) identified every possible combination of the eight most-common cardiac conditions. Both CNN-dig and CNN-ima accurately (98%) detected AF from standard 12-lead ECG digital signals and images, respectively. Similar classification accuracy was achieved with images containing smartphone camera acquisition artifacts. Automated detection of cardiac conditions in standard digital or image 12-lead ECG signals is feasible and may improve current diagnostic methods.

Indexed as

Diagnosis, Computer-AssistedImage Interpretation, Computer-AssistedAtrial FibrillationAutomationElectrocardiographyFemaleHeartHeart DiseasesHumansMaleNeural Networks, ComputerReproducibility of ResultsSensitivity and SpecificitySupervised Machine Learning

Identifiers

PMID33004907
PMCPMC7530668
OpenAlexW3090145920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.