ArticleNature communications2020
Genomics of the Argentinian cholera epidemic elucidate the contrasting dynamics of epidemic and endemic Vibrio cholerae.
Article in Nature communications, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed, 27 citations in OpenAlex.
- Interspecies Exchange of Mobile Genetic Elements During a Plant Disease Outbreak.Genome biology and evolution · 2026Article
- Pandemic Vibrio cholerae and the Environmental Reservoir Hypothesis-Outstanding Questions Central to Global Cholera Control.Environmental microbiology · 2026Article
- Population structure and phylogenetic analysis of Vibrio cholerae non-O1/O139 by whole genome sequencing.PloS one · 2026Article
- Inference of Multiple Mergers while Dating a Pathogen Phylogeny.Systematic biology · 2025Article
- Allelic variations and gene cluster modularity act as nonlinear bottlenecks for cholera emergence.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- West African-South American pandemic Vibrio cholerae encodes multiple distinct phage defence systems.Nature microbiology · 2025Article
- Non-O1/O139 environmental Vibrio cholerae from Northern Cameroon reveals potential intra-/inter-continental transmissions.PLoS neglected tropical diseases · 2025Article
- Surveillance of travel-associated isolates elucidates the diversity of non-pandemicMicrobial genomics · 2024Article
- Article
- Congruity of genomic and epidemiological data in modelling of local cholera outbreaks.Proceedings. Biological sciences · 2024Article
- Genomic epidemiology reveals multidrug resistant plasmid spread between Vibrio cholerae lineages in Yemen.Nature microbiology · 2023Article
- Article
- Reemergence of Cholera in Haiti.The New England journal of medicine · 2022Article
- Putting rapid tests to work in surveillance and control of cholera.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022Article
- Genomic contextualisation of ancient DNA molecular data from an Argentinian fifth pandemicMicrobial genomics · 2021Article
- Article
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Authors and funding
17 authors at 5 institutions in 3 countries.
Funding
Abstract
In order to control and eradicate epidemic cholera, we need to understand how epidemics begin, how they spread, and how they decline and eventually end. This requires extensive sampling of epidemic disease over time, alongside the background of endemic disease that may exist concurrently with the epidemic. The unique circumstances surrounding the Argentinian cholera epidemic of 1992-1998 presented an opportunity to do this. Here, we use 490 Argentinian V. cholerae genome sequences to characterise the variation within, and between, epidemic and endemic V. cholerae. We show that, during the 1992-1998 cholera epidemic, the invariant epidemic clone co-existed alongside highly diverse members of the Vibrio cholerae species in Argentina, and we contrast the clonality of epidemic V. cholerae with the background diversity of local endemic bacteria. Our findings refine and add nuance to our genomic definitions of epidemic and endemic cholera, and are of direct relevance to controlling current and future cholera epidemics.
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