Evidence map›Paper›PMID 33004782›Full record

ReviewActa bio-medica : Atenei Parmensis2020

Food allergy: an updated review on pathogenesis, diagnosis, prevention and management.

Mauro Calvani, Caterina Anania, Carlo Caffarelli, Alberto Martelli, Michele Miraglia Del Giudice, Claudio Cravidi, Marzia Duse, Sara Manti, Maria Angela Tosca, Fabio Cardinale and 3 more

Open access · greenAbstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
  2. Article
  3. Unusual Causes of Food-Induced Anaphylaxis - A Review.Indian dermatology online journal · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 12 institutions in 1 country.

Mauro CalvaniUOC di Pediatria. Azienda Ospedaliera S. Camillo Forlanini, Roma, Italy. maurocalvani58@gmail.com.
Caterina AnaniaDipartimento Materno Infantile e Scienze Urologiche, Policlinico Umberto I, "La Sapienza" Università di Roma, Italy. caterina.anania@uniroma1.it.
Carlo CaffarelliClinica Pediatrica, Dipartimento di Medicina e Chirurgia, Università di Parma, Italy. carlo.caffarelli@unipr.it.
Alberto MartelliDepartment of Pediatrics, G.Salvini Hospital, Garbagnate Milanese, Milan, Italy. agmartelli@asst-rhodense.it.
Michele Miraglia Del GiudiceDepartment of Woman, Child and of General and Specialized Surgery. University of Campania"Luigi Vanvitelli" Naples, Italy. michele.miraglia@unicampania.it.
Claudio CravidiAgenzia Tutela della Salute, ATS (National Healthcare System), Pavia, Italy. claudiocravidi@gmail.com.
Marzia DuseDepartment of Pediatrics, Sapienza University, Rome, Italy. marzia.duse@uniroma1.it.
Sara MantiUOC Broncopneumologia Pediatrica e Fibrosi Cistica, AOUP "Vittorio-Emanuele", San Marco Hospital, Università di Catania, Catania, Italy. saramanti@hotmail.it.
Maria Angela ToscaAllergy Center, Department of Pediatrics, Istituto G. Gaslini, Genoa, Italy. mariangelatosca@gaslini.org.
Fabio CardinaleDepartment of Pediatrics and Emergency, Pediatric Allergy and Pulmunology Unit, Azienda Ospedaliera-Universitaria Consorziale-Policlinico, Ospedale Pediatrico Giovanni XXIII, Bari, Italy.. fabiocardinale@libero.it.
Elena ChiappiniDivision of Paediatric Infectious Disease, Anna Meyer Children's University Hospital, Department of Health Sciences, University of Florence, Florence, Italy. elena.chiappini@unifi.it.
Francesca OliveroPediatric Clinic Department of Pediatrics, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy. francesca_ol@hotmail.it.
Gian Luigi MarsegliaPediatric Clinic Department of Pediatrics, Fondazione IRCCS Policlinico S. Matteo, University of Pavia, Pavia, Italy. gl.marseglia@smatteo.pv.it.
University of Pavia · ITAzienda Ospedaliera San Camillo-Forlanini · ITAzienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele · ITFatebenefratelli Hospital · ITIstituto Giannina Gaslini · ITMeyer Children's Hospital · ITMinistero della Salute · ITOspedale Pediatrico Giovanni XXIII · ITPoliclinico Umberto I · ITSapienza University of Rome · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Parma · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy (FA) is an adverse immunologic response triggered by normally innocuous food protein antigens.  FA can be broadly classified into those that are IgE mediated, those that are mediated by both IgE-dependent and IgE-independent pathways (mixed), and those that are not IgE mediated  Immunoglobulin E. (IgE)-mediated reaction is characterized by rapid onset of symptoms involving respiratory, gastrointestinal, dermatologic and cardiovascular systems; mixed and non-IgE-mediated has a longer onset and manifests primary in the gastrointestinal tract and skin. The diagnosis of food allergy is based on clinical history, diagnostic testing (skin prick test and allergen-specific IgE levels in the serum), elimination diet and, oral food challenge. In recent years the diagnosis and treatment of pediatric FA have notably improved. In the diagnostic pathway of FA an important recent innovation is the CRD introduction.  This resulted in the possibility of improving diagnostic accuracy through FA prediction severity and prognosis and thereby decreasing the OCF necessity. Recent studies emphasize the possibility of preventing FA through early introduction of food (peanuts and egg) to high-risk infants. FA management is based on avoidance of offending food and prompt treatment of allergic reaction. Currently under study are recently developed treatment approaches for FA management including specific OIT.

Indexed as

Food HypersensitivityAllergensChildFoodHumansImmunoglobulin EInfantSkin TestsAllergensImmunoglobulin E

Identifiers

PMID33004782
PMCPMC8023067
OpenAlexW3090716048

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.