Evidence map›Paper›PMID 33004659›Full record

ArticleJournal of epidemiology and community health2021

SARS-CoV-2 infection in London, England: changes to community point prevalence around lockdown time, March-May 2020.

Michael Edelstein, Chinelo Obi, Meera Chand, Susan Hopkins, Kevin Brown, Mary Ramsay

Open access · hybridAbstract read
In one paragraph

Article in Journal of epidemiology and community health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.

  1. Pooled it
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  6. Combined epidemiological and genomic analysis of nosocomial SARS-CoV-2 infection early in the pandemic and the role of unidentified cases in transmission.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Michael EdelsteinNational Infection Service, Public Health England, London, UK Michael.edelstein@phe.gov.uk.ORCID 0000-0002-7323-0806
Chinelo ObiNational Infection Service, Public Health England, London, UK.
Meera ChandNational Infection Service, Public Health England, London, UK.
Susan HopkinsNational Infection Service, Public Health England, London, UK.
Kevin BrownNational Infection Service, Public Health England, London, UK.
Mary RamsayNational Infection Service, Public Health England, London, UK.
Public Health England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe UK has been one of the European countries most affected by COVID-19 pandemic. The UK implemented a lockdown in March 2020, when testing policy at the time was focusing on hospitalised cases. Limited information is therefore available on the impact of the lockdown on point prevalence in the community. We assessed COVID-19 point prevalence in London between early April and early May 2020, which approximately reflect infection around the time of the lockdown and 3-5 weeks into lockdown.

methodsWe tested 1064 participants of a community surveillance cohort for acute COVID-19 infection using PCR in London in April and May 2020 and described positivity as well as characteristics and symptoms of the participants.

resultsPoint prevalence decreased from 2.2% (95% CI 1.4 to 3.5) in early April to 0.2% (95% CI 0.03 to 1.6) in early May. 22% of those who tested positive in April were asymptomatic. Extrapolation from reports of confirmed cases suggest that 5-7.6% of total infections were confirmed by testing during this period.

conclusionCOVID-19 point prevalence in the community sharply decreased after lockdown was implemented. This study is based on a small sample and regular seroprevalence studies are needed to better characterise population-level immunity.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionChildChild, PreschoolCOVID-19FemaleHumansLondonMaleMiddle AgedPandemicsPolymerase Chain ReactionPrevalencecommunicable diseasescontrol of diseasesEpidemics

Identifiers

PMID33004659
PMCPMC7815898
OpenAlexW3089573232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.